HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	27903893, 27835608, 29249800, 30446660, 21157430, 16725394, 19706771, 15107424, 20661446
Identification Methods	enzymatic study, affinity chromatography technology, pull down, unspecified method, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 303
+	Hs
		487258 ANDR_HUMAN (1-920): 0: 966: 100.00		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		183054 ANDR_HUMAN (1-920): 0: 966: 100.00		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		370707 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		377807 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1269930 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		370425 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		437655 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		414528 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		297019 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Mm
		59439 A3KN90_MOUSE (90-920): 4.3e-106: 353: 29.58		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Hs
		369237 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		297078 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Hs
		377203 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213442 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		858657 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		437629 MCR_HUMAN (401-920): 3.98e-106: 353: 38.18		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		414470 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213448 PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		183050 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		183143 ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02