HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.756

Property	Details
Experiments	11923464, 20812024, 22508987, 28611094, 12441355, 14593076, 34585037, 35785414, 15062576, 17356171
Identification Methods	affinity chromatography technology, pull down, proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 2514
+	Hs
		261380 ANDR_HUMAN (1-920): 0: 966: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		370824 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		487826 ANDR_HUMAN (1-920): 0: 966: 100.00		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		487804 ANDR_HUMAN (1-920): 0: 966: 100.00		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		487695 ANDR_HUMAN (1-920): 0: 966: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		487596 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		261369 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261370 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		370417 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TARA_HUMAN (40-1577): 3.75e-52: 206: 9.68
+	Hs
		370728 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		377792 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		377762 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		RCOR3_HUMAN (351-810): 1.25e-41: 163: 20.65
+	Hs
		377537 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		MUC16_HUMAN (2-2512): 2.7e-35: 151: 7.92
+	Hs
		370263 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		370251 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		370040 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		370105 ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61
+	Hs
		377624 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		377615 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		377539 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61