Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: ALX1 (Q15699)
ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1)
Gene: ALX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.606

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 462
Hs

1 326
+ Dm
+ Mm
+ Dm
+ Hs
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024