HitPredict

Interactor 1: RARA (P10276)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: PRAM (Q96QH2)
PML-RARA-regulated adapter molecule 1 (PRAM) (PRAM-1)
Gene: PRAM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27419624, 21803845
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 462 Hs			1 670
+	Hs
		369815 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		NIPBL_HUMAN (5-529): 5.09e-30: 129: 15.22
+	Hs
		782571 HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52		NIPBL_HUMAN (5-529): 5.09e-30: 129: 15.22
+	Mm
		581219 THB_MOUSE (50-416): 9.21e-119: 357: 35.12		NFH_MOUSE (6-537): 9.87e-30: 128: 13.25
+	Hs
		1154059 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		NIPBL_HUMAN (5-529): 5.09e-30: 129: 15.22
+	Mm
		101828 ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05		F8WI37_MOUSE (9-572): 1.71e-22: 105: 17.94
+	Mm
		1142676 ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05		KMT2C_MOUSE (9-572): 1.68e-22: 105: 17.94
+	Hs
		369607 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		MDC1_HUMAN (7-492): 1.3e-12: 73.6: 5.75
+	Hs
		782707 HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52		CABIN_HUMAN (81-587): 4.47e-11: 68.4: 13.60
+	Hs
		1186078 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		MICA3_HUMAN (7-607): 4.97e-21: 100: 14.79
+	Hs
		152573 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		KMT2D_HUMAN (55-579): 4e-09: 62.3: 16.20
+	Hs
		370040 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		KMT2C_HUMAN (23-560): 4.84e-09: 62.2: 15.58
+	Hs
		370105 ESR1_HUMAN (5-460): 2.32e-119: 362: 21.81		TITIN_HUMAN (24-494): 4.16e-09: 62.2: 14.91
+	Hs
		152605 HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52		KMT2D_HUMAN (55-579): 4e-09: 62.3: 16.20
+	Hs
		782595 HNF4A_HUMAN (61-462): 6.66e-120: 360: 24.52		KMT2C_HUMAN (23-560): 4.84e-09: 62.2: 15.58
+	Hs
		152603 PPARG_HUMAN (66-416): 9.52e-115: 348: 30.26		KMT2D_HUMAN (55-579): 4e-09: 62.3: 16.20
+	Hs
		740556 PPARG_HUMAN (66-416): 9.52e-115: 348: 30.26		KMT2C_HUMAN (23-560): 4.84e-09: 62.2: 15.58
+	Hs
		1056909 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		MDC1_HUMAN (7-492): 1.3e-12: 73.6: 5.75
+	Mm
		1142660 ERR2_MOUSE (5-417): 5.86e-110: 333: 27.05		KMT2D_MOUSE (26-619): 2.22e-10: 66.6: 9.73
+	Hs
		517813 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		NFH_HUMAN (11-364): 4.33e-11: 68.4: 15.25
+	Hs
		152674 ESR2_HUMAN (3-447): 3.53e-106: 327: 24.89		KMT2D_HUMAN (55-579): 4e-09: 62.3: 16.20