HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: KI2S2 (P43631)
Killer cell immunoglobulin-like receptor 2DS2 (CD158 antigen-like family member J) (NK receptor 183 ActI) (Natural killer-associated transcript 5) (NKAT-5) (p58 natural killer cell receptor clone CL-49) (p58 NK receptor CL-49) (CD antigen CD158j)
Gene: KIR2DS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11172020
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 304
+	Hs
		798280 Q5S3G3_HUMAN (1-365): 2.13e-176: 496: 81.92		KI2S4_HUMAN (1-304): 4.73e-117: 340: 91.78
+	Hs
		798195 Q5S3G3_HUMAN (1-365): 2.13e-176: 496: 81.92		KI2L3_HUMAN (1-304): 9.06e-110: 323: 95.72
+	Hs
		798194 Q5RIP0_HUMAN (1-366): 3.87e-168: 475: 90.98		KI2L3_HUMAN (1-304): 9.06e-110: 323: 95.72
+	Hs
		798173 Q5RIP0_HUMAN (1-366): 3.87e-168: 475: 90.98		KI2L2_HUMAN (1-303): 8.23e-107: 316: 95.71
+	Hs
		798148 Q5RIP0_HUMAN (1-366): 3.87e-168: 475: 90.98		KI2L1_HUMAN (1-303): 7.68e-106: 314: 91.09
+	Hs
		798171 Q5D1W8_HUMAN (1-366): 2.02e-167: 473: 90.98		KI2L2_HUMAN (1-303): 8.23e-107: 316: 95.71
+	Hs
		798146 Q5D1W8_HUMAN (1-366): 2.02e-167: 473: 90.98		KI2L1_HUMAN (1-303): 7.68e-106: 314: 91.09
+	Hs
		382484 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		LIRB4_HUMAN (1-304): 1.14e-71: 229: 30.60
+	Hs
		1060406 Q95J06_HUMAN (1-365): 0: 509: 79.73		KI3S1_HUMAN (1-251): 4.2e-57: 190: 38.19
+	Hs
		47499 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		A0A8I5QEB2_HUMAN (1-246): 1.42e-60: 200: 42.17
+	Hs
		382420 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		KI3S1_HUMAN (1-251): 4.2e-57: 190: 38.19
+	Hs
		382341 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		KI3L2_HUMAN (1-246): 2.89e-56: 189: 40.96
+	Hs
		798244 Q5S3G3_HUMAN (1-365): 2.13e-176: 496: 81.92		KI3L2_HUMAN (1-246): 2.89e-56: 189: 40.96
+	Hs
		1060403 Q5SUL5_HUMAN (1-365): 1.81e-174: 491: 80.00		KI3S1_HUMAN (1-251): 4.2e-57: 190: 38.19
+	Hs
		1245576 Q95J06_HUMAN (1-365): 0: 509: 79.73		LIRB1_HUMAN (21-246): 1.28e-39: 148: 37.66
+	Hs
		1130838 Q5S3G3_HUMAN (1-365): 2.13e-176: 496: 81.92		LIRB1_HUMAN (21-246): 1.28e-39: 148: 37.66
+	Hs
		382485 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		LIRB1_HUMAN (21-246): 1.28e-39: 148: 37.66
+	Hs
		1232786 Q95J06_HUMAN (1-365): 0: 509: 79.73		LIRB2_HUMAN (10-138): 5.62e-15: 77.1: 36.43
+	Hs
		1130837 Q5S3G3_HUMAN (1-365): 2.13e-176: 496: 81.92		LIRB2_HUMAN (10-138): 5.62e-15: 77.1: 36.43
+	Hs
		382478 HLAA_HUMAN (1-365): 1.85e-176: 496: 81.37		LIRB2_HUMAN (10-138): 5.62e-15: 77.1: 36.43