HitPredict

Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Interactor 2: RCN2 (Q14257)
Reticulocalbin-2 (Calcium-binding protein ERC-55) (E6-binding protein) (E6BP)
Gene: RCN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	25852190, 29777862
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 317
+	Hs
		216152 ARAF_HUMAN (1-606): 0: 579: 100.00		CALU_HUMAN (1-313): 5.78e-60: 195: 35.51
+	Hs
		488723 ARAF_HUMAN (1-606): 0: 579: 100.00		RCN1_HUMAN (31-317): 1.33e-49: 169: 37.98
+	Hs
		488791 ARAF_HUMAN (1-606): 0: 579: 100.00		CAB45_HUMAN (32-311): 7.3e-49: 168: 24.07
+	Hs
		216136 RAF1_HUMAN (13-606): 0: 534: 60.53		CALU_HUMAN (1-313): 5.78e-60: 195: 35.51
+	Hs
		374226 RAF1_HUMAN (13-606): 0: 534: 60.53		RCN2_HUMAN (1-317): 1.81e-55: 184: 100.00
+	Hs
		374782 RAF1_HUMAN (13-606): 0: 534: 60.53		CAB45_HUMAN (32-311): 7.3e-49: 168: 24.07
+	Hs
		488819 ARAF_HUMAN (1-606): 0: 579: 100.00		CALL5_HUMAN (152-287): 4.49e-09: 56.2: 26.47
+	Hs
		1217981 KSR1_HUMAN (50-606): 7.14e-122: 384: 24.24		CAB45_HUMAN (32-311): 7.3e-49: 168: 24.07
+	Dm
		1096613 Q24171_DROME (194-584): 1.1e-49: 187: 33.10		Q8IRH7_DROME (123-311): 4.41e-50: 166: 33.85
+	At
		483118 Q93ZU3_ARATH (263-572): 3.79e-38: 152: 33.23		CALM4_ARATH (219-316): 3.11e-15: 73.5: 23.47