Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2
Interactor 2: BAD (Q92934)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9305851, 16697956, 33961781, 15990872, 20603619, 10611223, 15694340, 7834748, 15849194, 9388232, 17446862, 9463381 |
| Identification Methods | far western blotting, pull down, unspecified method, affinity chromatography technology, two hybrid, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~Bcl-2_BAD |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0006915 - apoptotic process and 7 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
