HitPredict

Interactor 1: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1907 Hs			1 232
+	Hs
		489937 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		489933 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		489923 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		489942 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		489932 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		489896 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		489936 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		489951 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436131 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		489940 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120286 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		893964 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852459 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		925247 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892348 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		490024 PTPRF_HUMAN (1-1907): 0: 1662: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		900436 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		436285 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915648 PTPRS_HUMAN (1-1907): 0: 1581: 65.73		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		617091 PTPRG_HUMAN (909-1904): 0: 737: 27.21		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15