HitPredict

Interactor 1: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Interactor 2: FKBP3 (P38911)
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding nuclear protein) (FKBP-70) (Nucleolar proline isomerase) (Proline rotamase)
Gene: FPR3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.608

Property	Details
Experiments	26217697, 25452130, 19536198, 23217712
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 642 Sc			1 411
+	Sc
		605348 HSP74_YEAST (1-642): 0: 961: 81.09		FKBP3_YEAST (1-411): 1.34e-108: 327: 100.00
+	Sc
		492494 HSP71_YEAST (1-642): 0: 925: 100.00		FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16
+	Sc
		495006 HSP72_YEAST (1-642): 0: 922: 96.26		FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16
+	Sc
		493951 HSP72_YEAST (1-642): 0: 922: 96.26		FKBP3_YEAST (1-411): 1.34e-108: 327: 100.00
+	Hs
		713959 HS71L_HUMAN (2-642): 0: 949: 72.52		FKBP5_HUMAN (168-410): 1.69e-56: 194: 17.65
+	Hs
		504028 HSP7C_HUMAN (2-642): 0: 937: 73.91		FKBP5_HUMAN (168-410): 1.69e-56: 194: 17.65
+	Hs
		503930 HSP7C_HUMAN (2-642): 0: 937: 73.91		FKBP4_HUMAN (168-410): 1.05e-49: 176: 18.29
+	Sc
		589262 HSP74_YEAST (1-642): 0: 961: 81.09		FKBP_YEAST (301-410): 2.19e-44: 151: 46.02
+	Nc
		223821 HSP70_NEUCR (1-642): 0: 950: 80.50		FKBP2_NEUCR (319-409): 4.59e-38: 138: 39.79
+	Hs
		503907 HSP7C_HUMAN (2-642): 0: 937: 73.91		FKBP3_HUMAN (239-410): 9.26e-43: 151: 31.15
+	Sc
		490642 HSP71_YEAST (1-642): 0: 925: 100.00		FKBP2_YEAST (304-411): 1.66e-47: 160: 45.95
+	Sc
		493453 HSP72_YEAST (1-642): 0: 922: 96.26		FKBP2_YEAST (304-411): 1.66e-47: 160: 45.95
+	Sc
		449903 HSP73_YEAST (1-642): 0: 925: 79.05		FKBP_YEAST (301-410): 2.19e-44: 151: 46.02
+	Sc
		490302 HSP71_YEAST (1-642): 0: 925: 100.00		FKBP_YEAST (301-410): 2.19e-44: 151: 46.02
+	Sc
		493170 HSP72_YEAST (1-642): 0: 922: 96.26		FKBP_YEAST (301-410): 2.19e-44: 151: 46.02
+	Hs
		504536 HSP7C_HUMAN (2-642): 0: 937: 73.91		FKB10_HUMAN (308-411): 1.7e-29: 122: 33.02