HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16429126, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0016887 - ATP hydrolysis activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 769
+	Sc
		491210 HSP71_YEAST (1-639): 0: 969: 97.04		MLH1_YEAST (1-769): 0: 866: 100.00
+	Hs
		503588 HSP7C_HUMAN (2-639): 0: 948: 74.34		MLH1_HUMAN (1-769): 0: 840: 36.41
+	Sc
		493080 HSP72_YEAST (1-639): 0: 935: 100.00		PMS1_YEAST (4-508): 5.46e-125: 396: 23.21
+	Sc
		492621 HSP71_YEAST (1-639): 0: 969: 97.04		MLH2_YEAST (3-546): 3.3e-112: 357: 21.65
+	Sc
		495115 HSP72_YEAST (1-639): 0: 935: 100.00		MLH2_YEAST (3-546): 3.3e-112: 357: 21.65