HitPredict

Interactor 1: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Interactor 2: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	35417483, 19536198, 16429126
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 639 Sc			1 345
+	Sc
		456670 HSP71_YEAST (1-639): 0: 969: 97.04		RIR2_YEAST (2-345): 4.69e-156: 445: 54.47
+	Hs
		503525 HSP7C_HUMAN (2-639): 0: 948: 74.34		RIR2_HUMAN (20-345): 9.51e-163: 461: 47.40
+	Hs
		871637 HSP72_HUMAN (2-639): 0: 933: 71.23		RIR2B_HUMAN (8-345): 4.91e-159: 450: 45.03
+	Sc
		491790 HSP71_YEAST (1-639): 0: 969: 97.04		RIR4_YEAST (1-345): 5.01e-144: 412: 100.00
+	Sc
		456671 HSP72_YEAST (1-639): 0: 935: 100.00		RIR2_YEAST (2-345): 4.69e-156: 445: 54.47
+	Sc
		450107 HSP73_YEAST (1-639): 0: 961: 78.89		RIR4_YEAST (1-345): 5.01e-144: 412: 100.00