Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 17045592, 7931292, 16446437, 35063084
Identification Methods enzymatic study, protein kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0030424 - axon
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 758
Hs

1 483
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024