Protein: CRP
DNA-binding transcriptional dual regulator CRP (Catabolite activator protein) (CAP) (Catabolite gene activator) (cAMP receptor protein) (CRP) (cAMP regulatory protein) (cAMP-activated global transcriptional regulator CRP)

Gene: CRP
Organism: Escherichia coli K-12
Interactions: 40
UniProt ID: P0ACJ8

Gene Ontology (top 5):
GO:0003680 - minor groove of adenine-thymine-rich DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005829 - cytosol
GO:0006351 - DNA-templated transcription
GO:0008301 - DNA binding, bending

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499247

CRP
DNA-binding transcriptional dual regulator CRP

4

17

Small-scale

0.896

High

365823

RPOD
RNA polymerase sigma factor RpoD

1

3

High-throughput

0.698

High

499253

NUSG
Transcription termination/antitermination protein NusG

1

0

High-throughput

0.558

High

395183

LYSR
Transcriptional activator protein LysR

1

1

High-throughput

0.541

High

496593

GCVA
Glycine cleavage system transcriptional activator

1

1

High-throughput

0.541

High

499269

YFGD
Uncharacterized protein YfgD

1

1

High-throughput

0.541

High

450010

MALT
HTH-type transcriptional regulator MalT

1

0

High-throughput

0.518

High

495602

MATP
Macrodomain Ter protein

1

0

High-throughput

0.518

High

495740

RRAA
Regulator of ribonuclease activity A

1

0

High-throughput

0.518

High

499197

HSLR
Heat shock protein 15

1

0

High-throughput

0.518

High

499248

CYTR
HTH-type transcriptional repressor CytR

1

0

High-throughput

0.518

High

499250

CAIF
Transcriptional activatory protein CaiF

1

0

High-throughput

0.518

High

499251

MTLR
Mannitol operon repressor

1

0

High-throughput

0.518

High

499261

FRLR
Probable fructoselysine utilization operon transcriptional repressor

1

0

High-throughput

0.518

High

499266

HYFR
DNA-binding transcriptional activator HyfR

1

0

High-throughput

0.518

High

492492

RL7
Large ribosomal subunit protein bL12

1

0

High-throughput

0.513

High

497763

ARTP
Arginine transport ATP-binding protein ArtP

1

1

High-throughput

0.494

High

499262

HEMW
Heme chaperone HemW

1

1

High-throughput

0.494

High

494266

RS5
Small ribosomal subunit protein uS5

1

2

High-throughput

0.484

High

499255

RCSB
Transcriptional regulatory protein RcsB

1

2

High-throughput

0.484

High

493238

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.464

High

499264

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.464

High

499265

NFUA
Fe/S biogenesis protein NfuA

1

0

High-throughput

0.458

High

489249

UBIB
Probable protein kinase UbiB

1

1

High-throughput

0.442

High

495270

YACL
UPF0231 protein YacL

3

0

High-throughput

0.351

High

499257

PRIC
Replication restart protein PriC

1

0

High-throughput

0.304

High

368277

CYAA
Adenylate cyclase

1

0

High-throughput

0.282

High

499249

YIBA
Protein YibA

1

0

High-throughput

0.282

High

499252

YIIR
Uncharacterized protein YiiR

1

0

High-throughput

0.282

High

499254

EMTA
Endo-type membrane-bound lytic murein transglycosylase A

1

0

High-throughput

0.282

High

499256

ENTD
Enterobactin synthase component D

1

0

High-throughput

0.282

High

499258

YHCA
Uncharacterized fimbrial chaperone YhcA

1

0

High-throughput

0.282

High

499259

EPTB
Kdo(2)-lipid A phosphoethanolamine 7''-transferase

1

0

High-throughput

0.282

High

499260

MLTB
Membrane-bound lytic murein transglycosylase B

1

0

High-throughput

0.282

High

499263

WECF
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

1

0

High-throughput

0.282

High

499267

ZAPC
Cell division protein ZapC

1

0

High-throughput

0.282

High

499270

ARNA
Bifunctional polymyxin resistance protein ArnA

1

0

High-throughput

0.282

High

499271

SUFS
Cysteine desulfurase

1

0

High-throughput

0.282

High

499268

YCGM
Oxaloacetate tautomerase YcgM

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025