Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 17932487, 26638075, 34079125, 26269332, 32814053
Identification Methods two hybrid, pull down, affinity chromatography technology, biochemical, proximity labelling technology, anti tag coimmunoprecipitation, validated two hybrid, anti bait coimmunoprecipitation, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005874 - microtubule
GO:0008017 - microtubule binding
GO:0015630 - microtubule cytoskeleton
and 6 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 758
Hs

1 1278
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024