Protein: PARC
DNA topoisomerase 4 subunit A (EC 5.6.2.2) (Topoisomerase IV subunit A)

Gene: PARC
Organism: Escherichia coli K-12
Interactions: 25
UniProt ID: P0AFI2

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005694 - chromosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

500850

MUKB
Chromosome partition protein MukB

4

2

Small-scale

0.706

High

500419

GYRA
DNA gyrase subunit A

1

6

High-throughput

0.625

High

500849

PARE
DNA topoisomerase 4 subunit B

1

12

High-throughput

0.625

High

500854

RL2
Large ribosomal subunit protein uL2

2

1

High-throughput

0.611

High

494794

SSRP
SsrA-binding protein

2

1

High-throughput

0.588

High

497333

MREB
Cell shape-determining protein MreB

2

6

High-throughput

0.588

High

500846

SSB
Single-stranded DNA-binding protein

2

1

High-throughput

0.571

High

492504

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.563

High

492732

RL1
Large ribosomal subunit protein uL1

1

1

High-throughput

0.536

High

500852

GRE1
Probable dehydratase PflD

1

0

High-throughput

0.513

High

469371

YCIH
Uncharacterized protein YciH

1

1

High-throughput

0.489

High

449850

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

3

High-throughput

0.484

High

492869

RL27
Large ribosomal subunit protein bL27

1

1

High-throughput

0.484

High

493245

RS10
Small ribosomal subunit protein uS10

1

1

High-throughput

0.484

High

493750

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.484

High

497016

DLDH
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.484

High

500855

RL22
Large ribosomal subunit protein uL22

1

1

High-throughput

0.484

High

491496

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

1

High-throughput

0.479

High

493094

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.464

High

496779

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.464

High

497495

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

500847

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.464

High

500848

MURF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

1

0

High-throughput

0.464

High

500851

WAAQ
Lipopolysaccharide heptosyltransferase 3

1

0

High-throughput

0.464

High

500853

YJJU
Uncharacterized protein YjjU

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025