HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ITIH4 (Q14624)
Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]
Gene: ITIH4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26402096
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 930
+	Hs
		496903 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ITIH3_HUMAN (17-928): 0: 863: 38.45
+	Hs
		497166 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		Q5T985_HUMAN (17-928): 0: 804: 31.30
+	Hs
		496275 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ITIH2_HUMAN (18-928): 0: 796: 31.33
+	Hs
		496634 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CA2D1_HUMAN (96-747): 1.13e-106: 357: 14.06