Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT
Interactor 2: HTRA1 (Q92743)
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)
Gene: HTRA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 0.55 | 0.649 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22535953, 26436840, 35063084 |
| Identification Methods | enzymatic study, protease assay, cosedimentation in solution, atomic force microscopy, transmission electron microscopy, isothermal titration calorimetry, fluorescence microscopy, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, protein cleavage, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005576 - extracellular region GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
