Protein: KSS1
Mitogen-activated protein kinase KSS1 (MAP kinase KSS1) (EC 2.7.11.24) (Kinase suppressor of SST2)

Gene: KSS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 175
UniProt ID: P14681

Gene Ontology (top 5):
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001402 - signal transduction involved in filamentous growth
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420008

STE7
Serine/threonine-protein kinase STE7

16

20

Small-scale

0.988

High

539307

STE11
Serine/threonine-protein kinase STE11

5

19

Small-scale

0.920

High

539331

STE5
Protein STE5

4

2

Small-scale

0.883

High

539343

MSG5
Tyrosine-protein phosphatase MSG5

4

20

Small-scale

0.881

High

539329

BEM3
GTPase-activating protein BEM3

3

6

Small-scale

0.857

High

365698

HSP82
ATP-dependent molecular chaperone HSP82

2

20

High-throughput

0.799

High

539291

KSS1
Mitogen-activated protein kinase KSS1

2

17

Small-scale

0.767

High

529986

STE12
Protein STE12

9

3

Small-scale

0.756

High

539402

DIG1
Down-regulator of invasive growth 1

8

2

Small-scale

0.755

High

539403

DIG2
Down-regulator of invasive growth 2

7

1

Small-scale

0.751

High

539296

FUS3
Mitogen-activated protein kinase FUS3

2

17

Small-scale

0.743

High

539334

PP2C1
Protein phosphatase 2C homolog 1

1

14

High-throughput

0.724

High

539337

KDX1
Serine/threonine-protein kinase KDX1

1

17

High-throughput

0.691

High

539429

ARP7
Actin-related protein 7

1

9

High-throughput

0.691

High

539300

TEC1
Ty transcription activator TEC1

3

2

Small-scale

0.667

High

539400

CDC14
Tyrosine-protein phosphatase CDC14

1

20

High-throughput

0.665

High

516786

SST2
Protein SST2

1

2

Small-scale

0.656

High

539378

DOHH
Deoxyhypusine hydroxylase

1

1

High-throughput

0.647

High

539397

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.647

High

539314

MAS5
Mitochondrial protein import protein MAS5

1

10

High-throughput

0.646

High

539324

RPN2
26S proteasome regulatory subunit RPN2

1

2

High-throughput

0.646

High

539398

ACT
Actin

1

8

High-throughput

0.646

High

539332

BCK2
Protein BCK2

2

1

High-throughput

0.628

High

539412

RGC1
Regulator of the glycerol channel 1

2

5

High-throughput

0.628

High

539318

MIG1
Regulatory protein MIG1

1

2

Small-scale

0.621

High

539387

MIG2
Regulatory protein MIG2

1

9

Small-scale

0.621

High

539312

NAP1
Nucleosome assembly protein

2

3

High-throughput

0.619

High

539372

SYEC
Glutamate--tRNA ligase, cytoplasmic

2

3

High-throughput

0.619

High

409877

CDC37
Hsp90 co-chaperone Cdc37

1

9

Small-scale

0.618

High

477097

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

7

High-throughput

0.618

High

539395

BNI4
Protein BNI4

2

1

Small-scale

0.586

High

539410

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.579

High

539356

TSC11
Target of rapamycin complex 2 subunit TSC11

2

2

High-throughput

0.574

High

389678

CDC25
Cell division control protein 25

1

3

Small-scale

0.561

High

539311

PTP1
Tyrosine-protein phosphatase 1

1

15

High-throughput

0.561

High

539326

TCA17
TRAPP-associated protein TCA17

1

1

High-throughput

0.541

High

539293

CATA
Peroxisomal catalase A

1

0

High-throughput

0.537

High

539316

POF1
Nicotinamide mononucleotide adenylyltransferase

1

0

High-throughput

0.537

High

539367

CAF16
CCR4-associated factor 16

1

0

High-throughput

0.537

High

539390

SNU71
U1 small nuclear ribonucleoprotein component SNU71

1

0

High-throughput

0.537

High

539418

NBA1
Protein NBA1

1

0

High-throughput

0.537

High

539422

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.537

High

393512

PMA1
Plasma membrane ATPase 1

1

6

High-throughput

0.536

High

505139

PYC1
Pyruvate carboxylase 1

1

4

High-throughput

0.536

High

539305

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.536

High

539325

CBS
Cystathionine beta-synthase

1

4

High-throughput

0.536

High

539338

LONM
Lon protease homolog, mitochondrial

1

8

High-throughput

0.536

High

539344

YHJ3
Uncharacterized protein YHR033W

1

1

High-throughput

0.536

High

539347

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.536

High

539352

TCPB
T-complex protein 1 subunit beta

1

16

High-throughput

0.536

High

539362

MKT1
Post-transcriptional regulator MKT1

1

1

High-throughput

0.536

High

539383

ASK10
Activator of SKN7 protein 10

1

5

High-throughput

0.536

High

539385

SYEM
Glutamate--tRNA ligase, mitochondrial

1

3

High-throughput

0.536

High

539399

SEN1
Helicase SEN1

1

1

High-throughput

0.536

High

539404

HAS1
ATP-dependent RNA helicase HAS1

1

6

High-throughput

0.536

High

539406

RUVB1
RuvB-like protein 1

1

7

High-throughput

0.536

High

539419

AVO1
Target of rapamycin complex 2 subunit AVO1

1

2

High-throughput

0.536

High

539379

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.513

High

539405

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.513

High

539425

RNH2C
Ribonuclease H2 subunit C

1

0

High-throughput

0.513

High

539351

MPT5
Suppressor protein MPT5

1

1

Small-scale

0.508

High

409941

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.501

High

482548

YA11A
Transposon Ty1-A Gag polyprotein

1

11

High-throughput

0.501

High

526936

TBP
TATA-box-binding protein

1

1

High-throughput

0.501

High

539308

SPT6
Transcription elongation factor SPT6

1

2

High-throughput

0.501

High

539320

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.501

High

539321

EF1G1
Elongation factor 1-gamma 1

1

7

High-throughput

0.501

High

539323

GLNA
Glutamine synthetase

1

1

High-throughput

0.501

High

539327

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

4

High-throughput

0.501

High

539330

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.501

High

539333

YBF5
Deoxyribonuclease Tat-D

1

1

High-throughput

0.501

High

539339

ADCS
Aminodeoxychorismate synthase

1

6

High-throughput

0.501

High

539345

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.501

High

539346

OSH7
Oxysterol-binding protein homolog 7

1

1

High-throughput

0.501

High

539355

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

4

High-throughput

0.501

High

539359

ASG1
Activator of stress genes 1

1

2

High-throughput

0.501

High

539360

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.501

High

539368

BUD27
Bud site selection protein 27

1

1

High-throughput

0.501

High

539370

IRC5
Uncharacterized ATP-dependent helicase IRC5

1

2

High-throughput

0.501

High

539373

ARC1
tRNA-aminoacylation cofactor ARC1

1

1

High-throughput

0.501

High

539380

ADK
Adenosine kinase

1

7

High-throughput

0.501

High

539384

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.501

High

539396

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.501

High

539416

BDF2
Bromodomain-containing factor 2

1

12

High-throughput

0.501

High

539421

SAS10
Something about silencing protein 10

1

1

High-throughput

0.501

High

539428

YD21A
Transposon Ty2-DR1 Gag polyprotein

1

10

High-throughput

0.501

High

539431

YN12A
Transposon Ty1-NL2 Gag polyprotein

1

11

High-throughput

0.501

High

539432

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.501

High

341900

ATPB
ATP synthase subunit beta, mitochondrial

1

11

High-throughput

0.500

High

360720

TBB
Tubulin beta chain

1

9

High-throughput

0.500

High

367680

EF1A
Elongation factor 1-alpha

1

7

High-throughput

0.500

High

381413

GAL1
Galactokinase

1

1

High-throughput

0.500

High

389209

HXKA
Hexokinase-1

1

3

High-throughput

0.500

High

423743

ATPA
ATP synthase subunit alpha, mitochondrial

1

11

High-throughput

0.500

High

424317

PYR1
Multifunctional protein URA2

1

9

High-throughput

0.500

High

454154

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.500

High

454540

TBA3
Tubulin alpha-3 chain

1

10

High-throughput

0.500

High

498420

METK1
S-adenosylmethionine synthase 1

1

4

High-throughput

0.500

High

539294

VATB
V-type proton ATPase subunit B

1

11

High-throughput

0.500

High

539295

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

12

High-throughput

0.500

High

539302

METK2
S-adenosylmethionine synthase 2

1

4

High-throughput

0.500

High

539304

HSP60
Heat shock protein 60, mitochondrial

1

10

High-throughput

0.500

High

539315

SRO9
RNA-binding protein SRO9

1

3

High-throughput

0.500

High

539317

CDC48
Cell division control protein 48

1

5

High-throughput

0.500

High

539328

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

1

High-throughput

0.500

High

539353

TCPD
T-complex protein 1 subunit delta

1

13

High-throughput

0.500

High

539365

TCPH
T-complex protein 1 subunit eta

1

13

High-throughput

0.500

High

539417

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

539424

HSP42
Heat shock protein 42

1

5

High-throughput

0.500

High

539430

RUVB2
RuvB-like protein 2

1

7

High-throughput

0.500

High

539292

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.489

High

539313

PHO84
Inorganic phosphate transporter PHO84

1

6

High-throughput

0.489

High

539349

HXT6
High-affinity hexose transporter HXT6

1

3

High-throughput

0.489

High

539427

RPN6
26S proteasome regulatory subunit RPN6

1

2

High-throughput

0.489

High

539411

CYK2
Cytokinesis protein 2

1

2

High-throughput

0.481

High

539297

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.480

High

539322

MLS1
Malate synthase 1

1

0

High-throughput

0.480

High

539336

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.480

High

539340

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

0

High-throughput

0.480

High

539342

HSM3
DNA mismatch repair protein HSM3

1

0

High-throughput

0.480

High

539361

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.480

High

539375

SIP4
Protein SIP4

1

0

High-throughput

0.480

High

539377

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.480

High

539386

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.480

High

539389

DUO1
DASH complex subunit DUO1

1

0

High-throughput

0.480

High

539393

REXO1
RNA exonuclease 1

1

0

High-throughput

0.480

High

539394

CAF40
Protein CAF40

1

0

High-throughput

0.480

High

539401

RNT1
Ribonuclease 3

1

0

High-throughput

0.480

High

539409

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.480

High

539426

HIF1
HAT1-interacting factor 1

1

0

High-throughput

0.480

High

539434

TAD3
tRNA-specific adenosine deaminase subunit TAD3

1

0

High-throughput

0.480

High

500295

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

2

Small-scale

0.479

High

539319

TF2B
Transcription initiation factor IIB

1

9

High-throughput

0.479

High

539364

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.479

High

539335

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

539350

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

Small-scale

0.458

High

539376

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.458

High

539298

PDI
Protein disulfide-isomerase

1

4

High-throughput

0.457

High

539310

YSP3
Subtilisin-like protease 3

1

1

High-throughput

0.457

High

539348

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

15

High-throughput

0.457

High

539358

VPS27
Vacuolar protein sorting-associated protein 27

1

3

High-throughput

0.457

High

539369

HXT10
Hexose transporter HXT10

1

4

High-throughput

0.457

High

539392

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.457

High

539407

YHM2
Citrate/oxoglutarate carrier protein

1

16

High-throughput

0.457

High

539408

ARA2
D-arabinose 1-dehydrogenase

1

2

High-throughput

0.457

High

539420

DGAT2
Diacylglycerol O-acyltransferase 1

1

3

High-throughput

0.457

High

378266

LEU3
3-isopropylmalate dehydrogenase

1

5

High-throughput

0.457

High

520776

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.457

High

520895

G6PI
Glucose-6-phosphate isomerase

1

2

High-throughput

0.457

High

539299

ADT2
ADP,ATP carrier protein 2

1

11

High-throughput

0.457

High

539301

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.457

High

539309

MPCP
Mitochondrial phosphate carrier protein

1

13

High-throughput

0.457

High

539371

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

477848

HSP77
Import motor subunit, mitochondrial

1

18

High-throughput

0.445

High

539357

SSB2
Ribosome-associated molecular chaperone SSB2

1

18

High-throughput

0.445

High

396171

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.438

High

539303

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.437

High

514608

FUS1
Nuclear fusion protein FUS1

1

2

Small-scale

0.417

High

539363

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.279

Low

539306

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.261

Low

539341

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

1

0

High-throughput

0.261

Low

539354

HPH2
Protein HPH2

1

0

High-throughput

0.261

Low

539366

EMP47
Protein EMP47

1

0

High-throughput

0.261

Low

539374

DLD2
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2

1

0

High-throughput

0.261

Low

539381

ABM1
Aberrant microtubules protein 1

1

0

High-throughput

0.261

Low

539382

YJ9J
Uncharacterized protein YJR142W

1

0

High-throughput

0.261

Low

539388

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.261

Low

539391

YG1A
Uncharacterized membrane protein YGR016W

1

0

High-throughput

0.261

Low

539413

PEX30
Peroxisomal membrane protein PEX30

1

0

High-throughput

0.261

Low

539414

CDA1
Chitin deacetylase 1

1

0

High-throughput

0.261

Low

539415

NVJ2
Nucleus-vacuole junction protein 2

1

0

High-throughput

0.261

Low

539423

SSF2
Ribosome biogenesis protein SSF2

1

0

High-throughput

0.261

Low

539433

VCX1
Vacuolar calcium ion transporter

1

0

High-throughput

0.261

Low

452944

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024