Protein: DBHB
DNA-binding protein HU-beta (HU-1) (NS1)

Gene: DBHB, hupB
Organism: Escherichia coli K-12
Interactions: 88
UniProt ID: P0ACF4

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005829 - cytosol
GO:0006270 - DNA replication initiation
GO:0006281 - DNA repair
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499045

DBHA
DNA-binding protein HU-alpha

5

13

Small-scale

0.932

High

490926

IHFA
Integration host factor subunit alpha

2

14

High-throughput

0.759

High

490961

IHFB
Integration host factor subunit beta

2

13

High-throughput

0.759

High

499101

DBHB
DNA-binding protein HU-beta

1

13

Small-scale

0.692

High

489300

ACP
Acyl carrier protein

3

0

High-throughput

0.616

High

382678

RS7
Small ribosomal subunit protein uS7

2

1

High-throughput

0.612

High

496761

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

2

2

High-throughput

0.612

High

499131

RL3
Large ribosomal subunit protein uL3

2

2

High-throughput

0.612

High

492595

RL19
Large ribosomal subunit protein bL19

2

1

High-throughput

0.611

High

361748

PHSM
Maltodextrin phosphorylase

2

1

High-throughput

0.588

High

490704

FIS
DNA-binding protein Fis

2

1

High-throughput

0.588

High

490878

HFQ
RNA-binding protein Hfq

2

1

High-throughput

0.588

High

494608

RPOA
DNA-directed RNA polymerase subunit alpha

2

1

High-throughput

0.588

High

494884

TGT
Queuine tRNA-ribosyltransferase

2

1

High-throughput

0.588

High

495328

UVRB
UvrABC system protein B

2

3

High-throughput

0.588

High

497079

DEAD
ATP-dependent RNA helicase DeaD

2

3

High-throughput

0.588

High

497269

ULAR
HTH-type transcriptional regulator UlaR

2

2

High-throughput

0.588

High

497378

CSPA
Cold shock protein CspA

2

5

High-throughput

0.588

High

497405

CSPC
Cold shock-like protein CspC

2

5

High-throughput

0.588

High

497616

RLUC
Ribosomal large subunit pseudouridine synthase C

2

4

High-throughput

0.588

High

497982

YBCJ
Putative RNA-binding protein YbcJ

2

2

High-throughput

0.588

High

499102

HNS
DNA-binding protein H-NS

2

1

High-throughput

0.588

High

499117

MALQ
4-alpha-glucanotransferase

2

1

High-throughput

0.588

High

499133

NFI
Endonuclease V

2

3

High-throughput

0.588

High

432418

T1SK
Type I restriction enzyme EcoKI specificity subunit

2

1

High-throughput

0.571

High

477383

T1MK
Type I restriction enzyme EcoKI methylase subunit

2

0

High-throughput

0.563

High

491490

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

499108

SKP
Chaperone protein Skp

2

0

High-throughput

0.563

High

499111

SEQA
Negative modulator of initiation of replication

2

0

High-throughput

0.563

High

499121

RDGC
Recombination-associated protein RdgC

2

0

High-throughput

0.563

High

499137

YBJX
Uncharacterized protein YbjX

2

1

High-throughput

0.537

High

491067

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.536

High

492714

RL1
Large ribosomal subunit protein uL1

1

2

High-throughput

0.536

High

493377

RS13
Small ribosomal subunit protein uS13

1

1

High-throughput

0.536

High

494068

RS4
Small ribosomal subunit protein uS4

1

3

High-throughput

0.536

High

499113

RL21
Large ribosomal subunit protein bL21

1

1

High-throughput

0.536

High

499114

DPO3A
DNA polymerase III subunit alpha

1

1

High-throughput

0.536

High

499118

NADE
NH(3)-dependent NAD(+) synthetase

1

1

High-throughput

0.536

High

499119

RHLE
ATP-dependent RNA helicase RhlE

1

3

High-throughput

0.536

High

499130

RL2
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

499126

FHUF
Ferric siderophore reductase

1

0

High-throughput

0.518

High

479650

VSR
DNA mismatch endonuclease Vsr

1

0

High-throughput

0.513

High

490811

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.513

High

491349

HTPG
Chaperone protein HtpG

1

0

High-throughput

0.513

High

493149

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.513

High

494429

RS9
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

499104

YEBG
Uncharacterized protein YebG

1

0

High-throughput

0.513

High

499112

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.513

High

499116

PEPD
Cytosol non-specific dipeptidase

1

0

High-throughput

0.513

High

499123

NFSB
Oxygen-insensitive NAD(P)H nitroreductase

1

0

High-throughput

0.513

High

499103

ROB
Right origin-binding protein

1

2

High-throughput

0.500

High

499124

USPG
Universal stress protein UP12

1

1

High-throughput

0.489

High

365873

DPO1
DNA polymerase I

1

1

High-throughput

0.484

High

395153

UVRD
DNA helicase II

1

2

High-throughput

0.484

High

444295

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.484

High

450095

RF2
Peptide chain release factor RF2

1

1

High-throughput

0.484

High

492233

PYRH
Uridylate kinase

1

1

High-throughput

0.484

High

494789

SSRP
SsrA-binding protein

1

1

High-throughput

0.484

High

499120

PQQL
Probable zinc protease PqqL

1

0

High-throughput

0.479

High

499128

YHHX
Uncharacterized oxidoreductase YhhX

1

0

High-throughput

0.479

High

499138

RLMI
Ribosomal RNA large subunit methyltransferase I

1

0

High-throughput

0.479

High

492268

QUEA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase

1

1

High-throughput

0.479

High

495560

TMAR
Pole-localizer protein TmaR

1

2

High-throughput

0.479

High

496874

P5CR
Pyrroline-5-carboxylate reductase

1

1

High-throughput

0.479

High

499105

KPYK1
Pyruvate kinase I

1

1

High-throughput

0.479

High

499122

RLUB
Ribosomal large subunit pseudouridine synthase B

1

4

High-throughput

0.479

High

499134

CSRA
Carbon storage regulator

1

1

High-throughput

0.479

High

499140

YNCE
Uncharacterized protein YncE

1

1

High-throughput

0.479

High

420142

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

0

High-throughput

0.464

High

498636

EXBB
Biopolymer transport protein ExbB

1

1

High-throughput

0.457

High

499110

YBBO
Uncharacterized oxidoreductase YbbO

1

2

High-throughput

0.457

High

497571

THIO
Thioredoxin 1

1

1

Small-scale

0.445

High

499115

SRLR
Glucitol operon repressor

1

2

High-throughput

0.442

High

499135

INSN1
Putative transposase InsN for insertion sequence element IS911A

1

0

High-throughput

0.438

High

432125

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

1

High-throughput

0.437

High

491933

RPPH
RNA pyrophosphohydrolase

1

1

High-throughput

0.437

High

499125

AG43
Antigen 43

1

1

High-throughput

0.437

High

499136

RLMF
Ribosomal RNA large subunit methyltransferase F

1

1

High-throughput

0.437

High

499141

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

2

0

High-throughput

0.313

High

499127

YRAN
UPF0102 protein YraN

2

0

High-throughput

0.307

High

499129

END8
Endonuclease 8

2

0

High-throughput

0.307

High

498780

SDHA
Succinate dehydrogenase flavoprotein subunit

1

0

High-throughput

0.279

Low

499109

NUOE
NADH-quinone oxidoreductase subunit E

1

0

High-throughput

0.279

Low

499132

YGHW
Uncharacterized protein YghW

1

0

High-throughput

0.279

Low

499139

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

0

High-throughput

0.279

Low

499106

YGGE
Uncharacterized protein YggE

1

0

High-throughput

0.261

Low

499107

CPXP
Periplasmic protein CpxP

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025