HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CTND2 (Q9UQB3)
Catenin delta-2 (Delta-catenin) (GT24) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin)
Gene: CTNND2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0050808 - synapse organization
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1225
+	Hs
		239029 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CTND1_HUMAN (302-1147): 1.93e-154: 490: 32.73
+	Hs
		238627 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA7_HUMAN (566-1026): 1.69e-106: 348: 12.53
+	Hs
		496219 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLAK_HUMAN (390-1115): 3.5e-100: 337: 15.92
+	Hs
		496430 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CTNB1_HUMAN (343-991): 1.86e-99: 336: 17.15
+	Hs
		168613 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA6_HUMAN (597-1021): 3.31e-100: 331: 13.29
+	Hs
		496611 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA5_HUMAN (597-1026): 3.23e-98: 325: 12.53
+	Hs
		239044 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		CTND1_HUMAN (302-1147): 1.93e-154: 490: 32.73
+	Rn
		582019 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PLAK_RAT (390-1115): 9.96e-102: 341: 15.92
+	Rn
		94245 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PLAK_RAT (390-1115): 9.96e-102: 341: 15.92
+	Hs
		134829 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA3_HUMAN (454-973): 2.98e-71: 249: 13.99
+	Hs
		152599 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		CTNB1_HUMAN (343-991): 1.86e-99: 336: 17.15
+	Hs
		542170 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		PLAK_HUMAN (390-1115): 3.5e-100: 337: 15.92
+	Hs
		554276 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		CTNB1_HUMAN (343-991): 1.86e-99: 336: 17.15
+	Dm
		578747 Q9VPR2_DROME (127-757): 2.65e-20: 98.2: 10.23		ARM_DROME (403-1030): 2.79e-87: 304: 16.84
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (5-481): 1.38e-11: 71.6: 13.88