Protein: FTSH
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) (Cell division protease FtsH)

Gene: FTSH
Organism: Escherichia coli K-12
Interactions: 32
UniProt ID: P0AAI3

Gene Ontology (top 5):
GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497819

HFLC
Modulator of FtsH protease HflC

5

4

Small-scale

0.912

High

497820

HFLK
Modulator of FtsH protease HflK

3

4

Small-scale

0.834

High

497817

FTSH
ATP-dependent zinc metalloprotease FtsH

1

17

Small-scale

0.647

High

497839

COPA
Copper-exporting P-type ATPase

2

4

High-throughput

0.611

High

497821

EXBB
Biopolymer transport protein ExbB

2

0

High-throughput

0.559

High

497829

PPIB
Peptidyl-prolyl cis-trans isomerase B

2

2

High-throughput

0.549

High

491738

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

2

1

High-throughput

0.537

High

393872

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.513

High

497818

HYPB
Hydrogenase maturation factor HypB

1

0

High-throughput

0.513

High

497837

YPDE
Aminopeptidase YpdE

1

0

High-throughput

0.513

High

421036

FUMC
Fumarate hydratase class II

1

3

High-throughput

0.489

High

497822

SURA
Chaperone SurA

1

3

High-throughput

0.489

High

497836

EUTE
Acetaldehyde dehydrogenase

1

6

High-throughput

0.489

High

497838

YAJO
1-deoxyxylulose-5-phosphate synthase YajO

1

9

High-throughput

0.489

High

497830

YIDC
Membrane protein insertase YidC

1

3

Small-scale

0.479

High

497823

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.458

High

382673

RS7
Small ribosomal subunit protein uS7

1

2

High-throughput

0.442

High

496278

CSPE
Cold shock-like protein CspE

1

2

High-throughput

0.442

High

497827

RPOH
RNA polymerase sigma factor RpoH

1

0

Small-scale

0.426

High

492475

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.307

High

497826

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.307

High

497834

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.307

High

497835

NFI
Endonuclease V

2

0

High-throughput

0.307

High

494923

TIG
Trigger factor

1

0

High-throughput

0.279

Low

497824

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.279

Low

497828

PHOP
Transcriptional regulatory protein PhoP

1

0

High-throughput

0.279

Low

497831

HYI
Hydroxypyruvate isomerase

1

0

High-throughput

0.279

Low

497832

LPXH
UDP-2,3-diacylglucosamine hydrolase

1

0

High-throughput

0.279

Low

432416

T1SK
Type I restriction enzyme EcoKI specificity subunit

1

0

High-throughput

0.269

Low

497833

HEXR
HTH-type transcriptional regulator HexR

1

0

High-throughput

0.253

Low

497825

MTLR
Mannitol operon repressor

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025