Interactor 1: IL1B (P10749)
Interleukin-1 beta (IL-1 beta)
Gene: IL1B

Interactor 2: CASP3 (P70677)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 18725521
Identification Methods protease assay
Interaction Type cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0032496 - response to lipopolysaccharide
GO:0043065 - positive regulation of apoptotic process
GO:0043525 - positive regulation of neuron apoptotic process
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 269
Mm

1 277
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024