HitPredict

Interactor 1: RPA1 (P10964)
DNA-directed RNA polymerase I subunit RPA190 (EC 2.7.7.6) (DNA-directed RNA polymerase I 190 kDa polypeptide) (A190) (DNA-directed RNA polymerase I largest subunit)
Gene: RPA190

Interactor 2: RPA12 (P32529)
DNA-directed RNA polymerase I subunit RPA12 (A12) (A12.2) (DNA-directed RNA polymerase I 13.7 kDa polypeptide)
Gene: RPA12

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 11805826, 16554755, 16429126, 37968396, 24153184, 24307683, 11918799, 21048197
Identification Methods tandem affinity purification, affinity chromatography technology, x-ray crystallography
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_2~TFIIS_C, RNA_pol_Rpb1_3~TFIIS_C, RNA_pol_Rpb1_4~TFIIS_C, RNA_POL_M_15KD~RNA_pol_Rpb1_5, RNA_pol_Rpb1_5~TFIIS_C
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
GO:0006361 - transcription initiation at RNA polymerase I promoter
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1664
Sc

1 125
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+ Bt
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+ Dm
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+ Sc
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+ At
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+ At

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Last updated: 15 Jul 2024