Protein: RLUC
Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) (23S rRNA pseudouridine(955/2504/2580) synthase) (rRNA pseudouridylate synthase C) (rRNA-uridine isomerase C)

Gene: RLUC
Organism: Escherichia coli K-12
Interactions: 71
UniProt ID: P0AA39

Gene Ontology (top 5):
GO:0000455 - enzyme-directed rRNA pseudouridine synthesis
GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0009982 - pseudouridine synthase activity
GO:0120159 - rRNA pseudouridine synthase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497654

RLUE
Ribosomal large subunit pseudouridine synthase E

2

2

High-throughput

0.789

High

497641

RLUB
Ribosomal large subunit pseudouridine synthase B

1

3

High-throughput

0.724

High

493371

RS13
Small ribosomal subunit protein uS13

3

2

High-throughput

0.657

High

497622

RL17
Large ribosomal subunit protein bL17

3

3

High-throughput

0.657

High

497623

RL21
Large ribosomal subunit protein bL21

3

1

High-throughput

0.657

High

497640

RLMJ
Ribosomal RNA large subunit methyltransferase J

3

1

High-throughput

0.656

High

382672

RS7
Small ribosomal subunit protein uS7

2

4

High-throughput

0.628

High

494057

RS4
Small ribosomal subunit protein uS4

1

3

High-throughput

0.625

High

492704

RL1
Large ribosomal subunit protein uL1

2

3

High-throughput

0.612

High

497645

RL2
Large ribosomal subunit protein uL2

2

5

High-throughput

0.612

High

382564

RS6
Small ribosomal subunit protein bS6

2

1

High-throughput

0.611

High

492474

RL7
Large ribosomal subunit protein bL12

2

2

High-throughput

0.588

High

492590

RL19
Large ribosomal subunit protein bL19

2

2

High-throughput

0.588

High

492823

RL20
Large ribosomal subunit protein bL20

2

3

High-throughput

0.588

High

492909

RL28
Large ribosomal subunit protein bL28

2

1

High-throughput

0.588

High

493534

RS18
Small ribosomal subunit protein bS18

2

5

High-throughput

0.588

High

493614

RS20
Small ribosomal subunit protein bS20

2

1

High-throughput

0.588

High

496252

CSPD
Cold shock-like protein CspD

2

10

High-throughput

0.588

High

497398

CSPC
Cold shock-like protein CspC

2

10

High-throughput

0.588

High

497615

DBHA
DNA-binding protein HU-alpha

2

4

High-throughput

0.588

High

497616

DBHB
DNA-binding protein HU-beta

2

4

High-throughput

0.588

High

497621

SPOT
Bifunctional

2

1

High-throughput

0.588

High

497628

YHBY
RNA-binding protein YhbY

2

1

High-throughput

0.588

High

495803

RPOC
DNA-directed RNA polymerase subunit beta'

2

0

High-throughput

0.585

High

495889

RPOB
DNA-directed RNA polymerase subunit beta

2

0

High-throughput

0.585

High

497618

RL14
Large ribosomal subunit protein uL14

2

0

High-throughput

0.563

High

497631

RNR
Ribonuclease R

1

2

High-throughput

0.561

High

497632

SRMB
ATP-dependent RNA helicase SrmB

1

4

High-throughput

0.561

High

497633

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase PssA

1

1

High-throughput

0.561

High

497644

HRPA
ATP-dependent RNA helicase HrpA

1

1

High-throughput

0.561

High

497653

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

3

High-throughput

0.561

High

384015

RL15
Large ribosomal subunit protein uL15

2

2

High-throughput

0.558

High

497655

YNCE
Uncharacterized protein YncE

2

1

High-throughput

0.558

High

491930

RPPH
RNA pyrophosphohydrolase

2

1

High-throughput

0.537

High

497619

RL16
Large ribosomal subunit protein uL16

2

1

High-throughput

0.537

High

497625

RS14
Small ribosomal subunit protein uS14

2

3

High-throughput

0.537

High

494259

RS5
Small ribosomal subunit protein uS5

1

3

High-throughput

0.536

High

497620

ODP1
Pyruvate dehydrogenase E1 component

1

1

High-throughput

0.536

High

497634

RHLE
ATP-dependent RNA helicase RhlE

1

2

High-throughput

0.536

High

497646

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.536

High

496996

DLDH
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.513

High

497635

3PASE
Inorganic triphosphatase

1

1

High-throughput

0.512

High

497638

AIDB
Putative acyl-CoA dehydrogenase AidB

1

2

High-throughput

0.512

High

449834

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

6

High-throughput

0.489

High

493713

RS2
Small ribosomal subunit protein uS2

1

4

High-throughput

0.489

High

497642

USPF
Universal stress protein F

1

1

High-throughput

0.489

High

497643

USPG
Universal stress protein UP12

1

1

High-throughput

0.489

High

493143

RL9
Large ribosomal subunit protein bL9

1

5

High-throughput

0.484

High

493878

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.484

High

497074

DEAD
ATP-dependent RNA helicase DeaD

1

2

High-throughput

0.484

High

497374

CSPA
Cold shock protein CspA

1

10

High-throughput

0.484

High

497473

RL13
Large ribosomal subunit protein uL13

1

3

High-throughput

0.484

High

497613

YBCJ
Putative RNA-binding protein YbcJ

1

1

High-throughput

0.484

High

497617

YIBL
Uncharacterized protein YibL

1

2

High-throughput

0.484

High

497624

RL6
Large ribosomal subunit protein uL6

1

1

High-throughput

0.484

High

497626

RS1
Small ribosomal subunit protein bS1

1

3

High-throughput

0.484

High

497627

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

3

High-throughput

0.484

High

497629

RL18
Large ribosomal subunit protein uL18

1

1

High-throughput

0.484

High

497647

RL24
Large ribosomal subunit protein uL24

1

2

High-throughput

0.484

High

497648

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.484

High

497649

RL22
Large ribosomal subunit protein uL22

1

2

High-throughput

0.484

High

497650

RL5
Large ribosomal subunit protein uL5

1

1

High-throughput

0.484

High

497614

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

493472

RS16
Small ribosomal subunit protein bS16

1

4

High-throughput

0.442

High

494559

RNPA
Ribonuclease P protein component

1

1

High-throughput

0.437

High

497630

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.318

High

497652

YBJD
Uncharacterized protein YbjD

2

0

High-throughput

0.318

High

497636

YEDD
Uncharacterized lipoprotein YedD

1

0

High-throughput

0.279

Low

497637

MDTN
Multidrug resistance protein MdtN

1

0

High-throughput

0.279

Low

497639

PT1P
Phosphoenolpyruvate-dependent phosphotransferase system

1

0

High-throughput

0.279

Low

497651

PFLE
Putative pyruvate formate-lyase 3-activating enzyme

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025