HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: MAP1B (P46821)
Microtubule-associated protein 1B (MAP-1B) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1]
Gene: MAP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36042349, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 2468
+	Hs
		503643 HSP7C_HUMAN (26-637): 0: 916: 66.02		MAP1B_HUMAN (1-2468): 0: 950: 100.00
+	Hs
		564031 HSP76_HUMAN (25-635): 0: 915: 62.54		MAP1B_HUMAN (1-2468): 0: 950: 100.00
+	Hs
		501699 BIP_HUMAN (19-654): 0: 914: 100.00		APC_HUMAN (603-2214): 4.09e-44: 180: 9.80
+	Hs
		504619 HSP7C_HUMAN (26-637): 0: 916: 66.02		MINT_HUMAN (409-2424): 4.91e-24: 114: 7.64
+	Hs
		503916 HSP7C_HUMAN (26-637): 0: 916: 66.02		ANK2_HUMAN (1138-2400): 3.66e-21: 104: 9.91
+	Hs
		871747 HSP72_HUMAN (25-636): 0: 905: 64.51		MINT_HUMAN (409-2424): 4.91e-24: 114: 7.64
+	Hs
		501987 BIP_HUMAN (19-654): 0: 914: 100.00		ANK2_HUMAN (1138-2400): 3.66e-21: 104: 9.91
+	Hs
		483759 HS71A_HUMAN (26-635): 0: 911: 64.11		ANK2_HUMAN (1138-2400): 3.66e-21: 104: 9.91
+	Hs
		502734 BIP_HUMAN (19-654): 0: 914: 100.00		NCOR2_HUMAN (334-2072): 6.72e-15: 83.7: 6.77
+	Hs
		504482 HSP7C_HUMAN (26-637): 0: 916: 66.02		TITIN_HUMAN (362-1320): 1.1e-10: 69.8: 8.51