HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: VWCE (Q96DN2)
von Willebrand factor C and EGF domain-containing protein (HBV X protein up-regulated gene 11 protein) (HBxAg up-regulated gene 11 protein)
Gene: VWCE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 955
+	Hs
		502002 BIP_HUMAN (19-654): 0: 914: 100.00		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		314789 BIP_HUMAN (19-654): 0: 914: 100.00		MATN4_HUMAN (49-218): 1.33e-23: 108: 25.29
+	Hs
		502030 BIP_HUMAN (19-654): 0: 914: 100.00		FBLN3_HUMAN (46-217): 4.18e-18: 90.6: 25.26
+	Hs
		172781 BIP_HUMAN (19-654): 0: 914: 100.00		MATN3_HUMAN (34-184): 1.4e-11: 69.8: 18.52
+	Hs
		502294 BIP_HUMAN (19-654): 0: 914: 100.00		EGFL6_HUMAN (178-420): 1.37e-10: 67: 15.26
+	Hs
		502805 HSP7C_HUMAN (26-637): 0: 916: 66.02		LAMC1_HUMAN (50-416): 5.12e-09: 62.4: 11.50
+	Hs
		501606 BIP_HUMAN (19-654): 0: 914: 100.00		LAMC1_HUMAN (50-416): 5.12e-09: 62.4: 11.50