HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Hs			1 117
+	Hs
		713934 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		305992 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		714070 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		503785 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		564050 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		501893 BIP_HUMAN (19-654): 0: 914: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		305925 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		504734 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		305951 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		564180 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		305924 BIP_HUMAN (19-654): 0: 914: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		714074 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		714067 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		504756 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		564184 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		502557 BIP_HUMAN (19-654): 0: 914: 100.00		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		504720 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		564178 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		502528 BIP_HUMAN (19-654): 0: 914: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		483769 HS71A_HUMAN (26-635): 0: 911: 64.11		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62