Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5
Interactor 2: SIL1 (Q9H173)
Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP)
Gene: SIL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.60 | 0.750 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25877869, 28514442, 33961781, 29323281, 12356756, 36042349, 31258504, 24473200 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0051082 - unfolded protein binding |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Rn |   |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
