HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	33961781, 33957083, 30274258
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1827 Hs			1 351
+	Hs
		503264 MTAP2_HUMAN (1-1827): 0: 638: 100.00		KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88
+	Hs
		503263 MTAP2_HUMAN (1-1827): 0: 638: 100.00		KAPCG_HUMAN (1-351): 2.31e-162: 459: 82.91
+	Rn
		581976 TAU_RAT (1091-1827): 2.81e-57: 215: 25.10		KAPCB_RAT (1-351): 5.81e-161: 455: 92.31
+	Rn
		94199 F1LST4_RAT (1091-1826): 8.45e-57: 214: 25.00		KAPCB_RAT (1-351): 5.81e-161: 455: 92.31
+	Hs
		496248 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00
+	Mm
		397198 TAU_MOUSE (1114-1827): 2.74e-51: 197: 25.53		KAPCA_MOUSE (1-351): 4.96e-164: 463: 98.01
+	Hs
		496307 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88
+	Hs
		496305 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KAPCG_HUMAN (1-351): 2.31e-162: 459: 82.91
+	Hs
		496408 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		AKT2_HUMAN (18-343): 1.61e-150: 434: 38.79
+	Hs
		496407 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		AKT1_HUMAN (7-347): 2.89e-149: 430: 38.79
+	Bt
		337290 TAU_BOVIN (1457-1827): 2.6e-37: 149: 34.46		KAPCA_BOVIN (1-351): 6.13e-165: 466: 99.43
+	Hs
		496879 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KPCE_HUMAN (9-351): 6.36e-141: 418: 36.42
+	Hs
		496317 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		KS6B1_HUMAN (2-351): 1.99e-141: 412: 33.24
+	Hs
		116961 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		SGK1_HUMAN (34-342): 1.03e-85: 267: 42.54