HitPredict

Interactor 1: MTAP2 (P11137)
Microtubule-associated protein 2 (MAP-2)
Gene: MAP2

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	7820861
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048156 - tau protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1827 Hs			1 375
+	Hs
		497140 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		932156 MDC1_HUMAN (186-1801): 7.14e-66: 250: 10.01		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		1122431 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		ACTBL_HUMAN (2-375): 0: 735: 91.71
+	Hs
		496683 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Ce
		137705 O02592_CAEEL (1521-1804): 1.53e-53: 197: 27.67		ACT4_CAEEL (2-375): 0: 600: 97.59
+	Hs
		496806 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Mm
		498001 TAU_MOUSE (1114-1827): 2.74e-51: 197: 25.53		ACTC_MOUSE (2-375): 0: 592: 94.12
+	Hs
		496813 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		496816 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		496759 TAU_HUMAN (1069-1827): 1.92e-50: 195: 24.72		ACTA_HUMAN (2-375): 0: 591: 94.12
+	Ce
		501479 Q95QG4_CAEEL (1521-1789): 5.89e-45: 172: 28.26		ACT4_CAEEL (2-375): 0: 600: 97.59
+	Hs
		891686 MAP1A_HUMAN (112-1821): 1.34e-37: 157: 9.61		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Ce
		109402 H2KY94_CAEEL (1537-1790): 1.93e-31: 126: 22.22		ACT4_CAEEL (2-375): 0: 600: 97.59
+	Hs
		801071 KI67_HUMAN (62-1729): 1.72e-23: 111: 10.84		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		891853 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		929905 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932458 SRRM2_HUMAN (9-1815): 1.97e-19: 98.1: 8.82		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Dm
		54871 A1ZA72_DROME (85-1189): 1.82e-17: 91.8: 15.87		ACT6_DROME (2-375): 0: 594: 95.99
+	Hs
		932219 SRCAP_HUMAN (9-1700): 1.03e-17: 92.4: 8.10		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		932341 CIC_HUMAN (26-1666): 2.83e-15: 84.3: 9.15		ACTC_HUMAN (2-375): 0: 592: 94.12