HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: ARNT (P27540)
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Gene: ARNT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 27684187, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 789
+	Hs
		649072 HSP72_HUMAN (2-646): 0: 940: 85.47		ARNT_HUMAN (1-789): 0: 649: 100.00
+	Mm
		571858 HS71B_MOUSE (1-646): 0: 957: 83.90		HIF1A_MOUSE (74-788): 2.18e-137: 428: 16.99
+	Hs
		504148 HSP7C_HUMAN (1-646): 0: 967: 100.00		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		713985 HS71L_HUMAN (2-646): 0: 966: 82.48		HIF1A_HUMAN (82-787): 5.9e-129: 406: 17.48
+	Hs
		504066 HSP7C_HUMAN (1-646): 0: 967: 100.00		SIM2_HUMAN (90-751): 1.99e-121: 381: 17.35
+	Hs
		871577 HSP72_HUMAN (2-646): 0: 940: 85.47		NCOA2_HUMAN (67-741): 1.06e-106: 359: 14.84
+	Hs
		504638 HSP7C_HUMAN (1-646): 0: 967: 100.00		NPAS1_HUMAN (49-640): 1.14e-101: 327: 15.82
+	Hs
		503558 HSP7C_HUMAN (1-646): 0: 967: 100.00		AHR_HUMAN (64-767): 5.39e-93: 311: 14.89