HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MINT (Q96T58)
Msx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)
Gene: SPEN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 3664
+	Hs
		871747 HSP72_HUMAN (2-646): 0: 940: 85.47		MINT_HUMAN (1-3664): 0: 1099: 100.00
+	Hs
		503916 HSP7C_HUMAN (1-646): 0: 967: 100.00		ANK2_HUMAN (809-3143): 4.11e-25: 118: 9.30
+	Hs
		483759 HS71A_HUMAN (1-646): 0: 948: 84.37		ANK2_HUMAN (809-3143): 4.11e-25: 118: 9.30
+	Hs
		505011 HSP7C_HUMAN (1-646): 0: 967: 100.00		PRC2C_HUMAN (1490-3644): 8.69e-16: 87.2: 7.55
+	Hs
		504019 HSP7C_HUMAN (1-646): 0: 967: 100.00		PABP4_HUMAN (6-131): 2.64e-15: 84.9: 15.03
+	Hs
		503332 HSP7C_HUMAN (1-646): 0: 967: 100.00		PABP1_HUMAN (6-156): 2.77e-09: 65.2: 13.48
+	Hs
		871844 HSP72_HUMAN (2-646): 0: 940: 85.47		PRC2C_HUMAN (1490-3644): 8.69e-16: 87.2: 7.55