HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: TTC1 (Q99614)
Tetratricopeptide repeat protein 1 (TPR repeat protein 1)
Gene: TTC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	30021884, 32687490, 10567422
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding GO:0051082 - unfolded protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 292
+	Hs
		504028 HSP7C_HUMAN (1-646): 0: 967: 100.00		FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20
+	Hs
		713959 HS71L_HUMAN (2-646): 0: 966: 82.48		FKBP5_HUMAN (5-273): 9.22e-47: 164: 17.20
+	Hs
		503930 HSP7C_HUMAN (1-646): 0: 967: 100.00		FKBP4_HUMAN (29-282): 8.06e-45: 159: 18.02
+	Mm
		926131 HSP7C_MOUSE (1-646): 0: 967: 99.85		PPP5_MOUSE (91-287): 7.88e-39: 144: 22.22
+	Hs
		503738 HSP7C_HUMAN (1-646): 0: 967: 100.00		PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23
+	Mm
		926144 HSP7C_MOUSE (1-646): 0: 967: 99.85		SGTA_MOUSE (55-238): 1.84e-39: 141: 25.65
+	Hs
		504875 HSP7C_HUMAN (1-646): 0: 967: 100.00		AIPL1_HUMAN (10-253): 2.19e-38: 140: 19.70
+	Hs
		564188 HSP76_HUMAN (6-646): 0: 955: 77.54		RPAP3_HUMAN (72-252): 7.36e-41: 151: 24.86
+	Hs
		503968 HSP7C_HUMAN (1-646): 0: 967: 100.00		PPID_HUMAN (19-251): 1.93e-37: 138: 17.07
+	Hs
		564043 HSP76_HUMAN (6-646): 0: 955: 77.54		PPP5_HUMAN (91-287): 1.25e-38: 143: 23.23
+	Hs
		564151 HSP76_HUMAN (6-646): 0: 955: 77.54		SGTB_HUMAN (47-292): 1.48e-39: 141: 19.51
+	Hs
		297027 HSP7C_HUMAN (1-646): 0: 967: 100.00		TOM70_HUMAN (120-215): 6.68e-14: 73.6: 39.58
+	Hs
		213468 HSP7C_HUMAN (1-646): 0: 967: 100.00		SGTA_HUMAN (39-204): 5.37e-14: 73: 13.25
+	Hs
		713982 HS71L_HUMAN (2-646): 0: 966: 82.48		TOM34_HUMAN (119-236): 1.86e-14: 73.9: 38.02
+	Hs
		1120567 Q53FA3_HUMAN (2-646): 0: 967: 82.33		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		504631 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		714055 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		564163 HSP76_HUMAN (6-646): 0: 955: 77.54		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	Hs
		483801 HS71B_HUMAN (1-646): 0: 948: 84.37		DNJC7_HUMAN (120-221): 1.37e-11: 66.6: 37.26
+	At
		1338008 HS704_ARATH (3-646): 0: 948: 76.35		HSOP1_ARATH (88-292): 2.53e-11: 65.7: 13.45