HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	33957083, 27684187, 25036637
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0016020 - membrane GO:0051085 - chaperone cofactor-dependent protein refolding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 375
+	Hs
		714084 HS71L_HUMAN (2-646): 0: 966: 82.48		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Hs
		504442 HSP7C_HUMAN (1-646): 0: 967: 100.00		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		714026 HS71L_HUMAN (2-646): 0: 966: 82.48		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		279272 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB5_HUMAN (109-250): 8.83e-46: 162: 36.62
+	Hs
		279280 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJB5_HUMAN (109-250): 8.83e-46: 162: 36.62
+	Hs
		504564 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30
+	Hs
		714049 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJA3_HUMAN (102-261): 2.09e-43: 158: 32.30
+	Hs
		257901 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		257928 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		504901 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB4_HUMAN (109-251): 1.7e-42: 153: 39.86
+	Hs
		503463 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42
+	Hs
		714088 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJB4_HUMAN (109-251): 1.7e-42: 153: 39.86
+	Hs
		636256 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42
+	Hs
		504431 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB8_HUMAN (110-249): 2.46e-42: 149: 36.11
+	Hs
		714022 HS71L_HUMAN (2-646): 0: 966: 82.48		DNJB8_HUMAN (110-249): 2.46e-42: 149: 36.11
+	Mm
		222719 HS71B_MOUSE (1-646): 0: 957: 83.90		DNJB6_MOUSE (110-362): 1.08e-42: 154: 26.39
+	Hs
		257907 HSP76_HUMAN (6-646): 0: 955: 77.54		DNJB6_HUMAN (110-215): 1.44e-43: 155: 47.71
+	Hs
		504474 HSP7C_HUMAN (1-646): 0: 967: 100.00		DNJB3_HUMAN (110-216): 5.31e-41: 143: 42.73
+	Hs
		504897 HSP7C_HUMAN (1-646): 0: 967: 100.00		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		714087 HS71L_HUMAN (2-646): 0: 966: 82.48		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66