HitPredict

Interactor 1: ODB2 (P11182)
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (BCKDH-E2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Gene: DBT

Interactor 2: MECR (Q9BV79)
Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) (Nuclear receptor-binding factor 1) (HsNrbf-1) (NRBF-1)
Gene: MECR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 373
+	Hs
		506008 ODB2_HUMAN (1-482): 0: 635: 100.00		PTGR3_HUMAN (34-320): 2.48e-51: 177: 23.92
+	Hs
		739088 ODO2_HUMAN (52-481): 3.5e-140: 412: 24.54		QOR_HUMAN (43-371): 5.63e-93: 282: 21.52
+	Hs
		739029 ODO2_HUMAN (52-481): 3.5e-140: 412: 24.54		FAS_HUMAN (19-373): 6.34e-80: 269: 19.78
+	Hs
		489734 ODP2_HUMAN (40-137): 9.92e-23: 103: 21.21		QOR_HUMAN (43-371): 5.63e-93: 282: 21.52