Protein: GRL1A
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA polymerase II subunit M) (Glutamate receptor-like protein 1A)

Gene: GRL1A, POLR2M
Organism: Homo sapiens
Interactions: 66
UniProt ID: P0CAP2

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0003711 - transcription elongation factor activity
GO:0005635 - nuclear envelope
GO:0005665 - RNA polymerase II, core complex
GO:0006368 - transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

505997

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

1

High-throughput

0.650

High

316246

RECQ5
ATP-dependent DNA helicase Q5

4

0

High-throughput

0.623

High

505995

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

0

High-throughput

0.623

High

505998

RPB2
DNA-directed RNA polymerase II subunit RPB2

4

0

High-throughput

0.623

High

506006

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

0

High-throughput

0.623

High

506017

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

4

0

High-throughput

0.623

High

506023

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

3

3

High-throughput

0.611

High

506033

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

3

High-throughput

0.611

High

138437

BIN1
Myc box-dependent-interacting protein 1

3

0

High-throughput

0.585

High

192778

RPB4
DNA-directed RNA polymerase II subunit RPB4

3

0

High-throughput

0.585

High

505994

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

0

High-throughput

0.585

High

505999

RPB9
DNA-directed RNA polymerase II subunit RPB9

3

0

High-throughput

0.585

High

506001

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

3

0

High-throughput

0.585

High

506007

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

0

High-throughput

0.585

High

506030

GPN2
GPN-loop GTPase 2

3

2

High-throughput

0.558

High

506031

GPN1
GPN-loop GTPase 1

3

2

High-throughput

0.558

High

506041

GPN3
GPN-loop GTPase 3

3

2

High-throughput

0.558

High

506014

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

2

2

High-throughput

0.552

High

506000

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

0

High-throughput

0.528

High

506016

SPT6H
Transcription elongation factor SPT6

2

0

High-throughput

0.528

High

506040

KLH13
Kelch-like protein 13

2

2

High-throughput

0.504

High

506013

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

506011

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

1

High-throughput

0.457

High

506005

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.445

High

506004

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.426

High

506042

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.426

High

239529

MED14
Mediator of RNA polymerase II transcription subunit 14

1

2

High-throughput

0.407

High

506012

KLH26
Kelch-like protein 26

1

2

High-throughput

0.407

High

506038

ASB6
Ankyrin repeat and SOCS box protein 6

1

1

High-throughput

0.407

High

506039

KLHL9
Kelch-like protein 9

1

2

High-throughput

0.407

High

506025

RPAP1
RNA polymerase II-associated protein 1

4

0

High-throughput

0.339

High

506008

MED21
Mediator of RNA polymerase II transcription subunit 21

3

0

High-throughput

0.319

High

335950

MED26
Mediator of RNA polymerase II transcription subunit 26

2

0

High-throughput

0.288

High

506022

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

0

High-throughput

0.288

High

506032

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

High-throughput

0.288

High

506037

PIHD1
PIH1 domain-containing protein 1

2

0

Small-scale

0.288

High

506002

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.261

Low

506003

CEBPG
CCAAT/enhancer-binding protein gamma

1

0

High-throughput

0.238

Low

506036

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.238

Low

48898

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.232

Low

187263

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.232

Low

219467

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.232

Low

228018

SSNA1
Microtubule nucleation factor SSNA1

1

0

High-throughput

0.232

Low

262474

MCE1
mRNA-capping enzyme

1

0

High-throughput

0.232

Low

287755

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.232

Low

305826

DXO
Decapping and exoribonuclease protein

1

0

High-throughput

0.232

Low

326291

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.232

Low

391172

FRIL
Ferritin light chain

1

0

High-throughput

0.232

Low

505991

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.232

Low

505992

CD19
B-lymphocyte antigen CD19

1

0

High-throughput

0.232

Low

505993

DCAM
S-adenosylmethionine decarboxylase proenzyme

1

0

High-throughput

0.232

Low

505996

SPR1B
Cornifin-B

1

0

High-throughput

0.232

Low

506009

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.232

Low

506010

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.232

Low

506015

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.232

Low

506018

CPNE2
Copine-2

1

0

High-throughput

0.232

Low

506019

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.232

Low

506020

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.232

Low

506021

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

506024

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.232

Low

506026

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.232

Low

506027

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.232

Low

506028

SFR19
Splicing factor, arginine/serine-rich 19

1

0

High-throughput

0.232

Low

506029

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.232

Low

506034

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.232

Low

506035

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025