HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29568061, 34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030036 - actin cytoskeleton organization GO:0032991 - protein-containing complex and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1271 Hs			1 586
+	Hs
		506531 BCR_HUMAN (1-1271): 0: 1005: 100.00		RADI_HUMAN (1-586): 7.83e-165: 484: 76.28
+	Hs
		506517 BCR_HUMAN (1-1271): 0: 1005: 100.00		PTN3_HUMAN (18-295): 2.55e-32: 134: 31.82
+	Hs
		547031 ABR_HUMAN (419-1271): 0: 567: 66.47		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		547074 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		1333741 ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07		E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28
+	Hs
		299235 VAV_HUMAN (393-1092): 5.12e-77: 275: 12.29		FARP2_HUMAN (2-548): 8.98e-114: 365: 19.42
+	Hs
		299283 Q96D37_HUMAN (393-1092): 1.17e-77: 275: 12.29		FARP2_HUMAN (2-548): 8.98e-114: 365: 19.42
+	Hs
		1333835 ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07		FARP1_HUMAN (3-549): 1.97e-117: 375: 19.07
+	Hs
		299236 CHIN_HUMAN (776-1248): 3.33e-78: 267: 18.99		FARP2_HUMAN (2-548): 8.98e-114: 365: 19.42
+	Hs
		547091 RHG21_HUMAN (1049-1216): 3.06e-23: 109: 40.00		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Hs
		547235 RHG35_HUMAN (1048-1214): 4.16e-20: 99.4: 31.74		EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00
+	Mm
		57881 KALRN_MOUSE (457-1087): 8.9e-58: 222: 14.39		E41L3_MOUSE (2-522): 3.29e-115: 366: 21.48
+	Hs
		640115 RHG21_HUMAN (1049-1216): 3.06e-23: 109: 40.00		MOES_HUMAN (1-586): 4.45e-161: 474: 72.70