Protein: PTPRC
Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (Lymphocyte antigen 5) (Ly-5) (T200) (CD antigen CD45)

Gene: PTPRC
Organism: Mus musculus
Interactions: 13
UniProt ID: P06800

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001779 - natural killer cell differentiation
GO:0001915 - negative regulation of T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0001960 - negative regulation of cytokine-mediated signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

411913

LCK
Proto-oncogene tyrosine-protein kinase LCK

2

20

Small-scale

0.755

High

420370

VAV
Proto-oncogene vav

1

12

Small-scale

0.575

High

420374

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.575

High

420379

Q91YX7
RAS p21 protein activator 1

1

11

Small-scale

0.575

High

420376

JAK2
Tyrosine-protein kinase JAK2

1

20

Small-scale

0.527

High

420372

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

1

High-throughput

0.479

High

420375

MRC1
Macrophage mannose receptor 1

1

5

Small-scale

0.479

High

420371

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.472

High

420368

CD44
CD44 antigen

1

2

Small-scale

0.445

High

420369

CBL
E3 ubiquitin-protein ligase CBL

1

7

High-throughput

0.445

High

420373

CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2

1

2

Small-scale

0.445

High

420377

SOS1
Son of sevenless homolog 1

1

1

Small-scale

0.445

High

420378

PTCA
Protein tyrosine phosphatase receptor type C-associated protein

1

1

Small-scale

0.445

High


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Last updated: 15 Jul 2024