HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0070062 - extracellular exosome GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1271 Hs			1 196
+	Hs
		506566 BCR_HUMAN (1-1271): 0: 1005: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		506561 BCR_HUMAN (1-1271): 0: 1005: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		436136 BCR_HUMAN (1-1271): 0: 1005: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		506557 BCR_HUMAN (1-1271): 0: 1005: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Mm
		925798 BCR_MOUSE (1-1271): 0: 941: 93.79		RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10
+	Hs
		900426 ABR_HUMAN (419-1271): 0: 567: 66.47		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915641 ABR_HUMAN (419-1271): 0: 567: 66.47		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Mm
		925793 ABR_MOUSE (419-1271): 0: 563: 66.00		RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10
+	Hs
		925527 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		925382 PREX2_HUMAN (483-1094): 2.85e-83: 302: 15.88		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		925455 PREX1_HUMAN (447-1058): 2.05e-83: 302: 15.70		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900616 PREX2_HUMAN (483-1094): 2.85e-83: 302: 15.88		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		900718 PREX1_HUMAN (447-1058): 2.05e-83: 302: 15.70		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		900786 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915891 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		951099 PREX2_HUMAN (483-1094): 2.85e-83: 302: 15.88		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		894323 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		894155 PREX2_HUMAN (483-1094): 2.85e-83: 302: 15.88		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		894238 PREX1_HUMAN (447-1058): 2.05e-83: 302: 15.70		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		894301 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49