Protein: ECD
Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1)

Gene: ECD
Organism: Homo sapiens
Interactions: 110
UniProt ID: O95905

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

327673

PRP8
Pre-mRNA-processing-splicing factor 8

8

1

Small-scale

0.754

High

327662

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

4

1

High-throughput

0.694

High

327691

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

2

High-throughput

0.694

High

271999

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

3

1

High-throughput

0.667

High

327670

EAPP
E2F-associated phosphoprotein

4

0

High-throughput

0.664

High

327726

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

4

0

High-throughput

0.664

High

327717

PIHD1
PIH1 domain-containing protein 1

2

1

Small-scale

0.662

High

327724

RUVB1
RuvB-like 1

2

1

Small-scale

0.654

High

327725

AAR2
Protein AAR2 homolog

5

1

High-throughput

0.652

High

327720

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.638

High

327706

TXNIP
Thioredoxin-interacting protein

2

0

Small-scale

0.625

High

327635

MYH7
Myosin-7

2

0

High-throughput

0.602

High

327664

TEBP
Prostaglandin E synthase 3

2

0

High-throughput

0.602

High

327710

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.602

High

327719

NCDN
Neurochondrin

2

0

High-throughput

0.602

High

327649

GSK3B
Glycogen synthase kinase-3 beta

2

1

High-throughput

0.601

High

327682

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.585

High

327718

TLS1
Splicing factor C9orf78

2

0

High-throughput

0.585

High

327701

WDR83
WD repeat domain-containing protein 83

2

2

High-throughput

0.574

High

327640

CTNA1
Catenin alpha-1

2

0

Small-scale

0.559

High

214451

MYO1B
Unconventional myosin-Ib

1

1

High-throughput

0.536

High

327659

MYO9B
Unconventional myosin-IXb

1

1

High-throughput

0.536

High

327667

OASL
2'-5'-oligoadenylate synthase-like protein

1

1

High-throughput

0.536

High

327680

SMYD4
SET and MYND domain-containing protein 4

1

1

High-throughput

0.536

High

327700

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.536

High

327672

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.529

High

327658

EWS
RNA-binding protein EWS

1

0

High-throughput

0.518

High

327648

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.515

High

175515

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.513

High

327631

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.513

High

327642

PSB10
Proteasome subunit beta type-10

1

0

High-throughput

0.513

High

327646

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

327650

RB27A
Ras-related protein Rab-27A

1

0

High-throughput

0.513

High

327653

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.513

High

327654

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

327655

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

327656

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

327668

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

327679

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

327687

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.513

High

327688

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

327703

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

327705

RBM38
RNA-binding protein 38

1

0

High-throughput

0.513

High

327711

AGO4
Protein argonaute-4

1

0

High-throughput

0.513

High

327633

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

327657

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.501

High

327643

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

162316

XPO1
Exportin-1

1

1

High-throughput

0.479

High

226179

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

313199

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.479

High

327638

GCFC2
Intron Large complex component GCFC2

1

1

High-throughput

0.479

High

327651

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

1

Small-scale

0.479

High

327671

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

327681

AHI1
Jouberin

1

4

High-throughput

0.479

High

327683

POC1A
POC1 centriolar protein homolog A

1

1

High-throughput

0.479

High

327696

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.479

High

327698

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.479

High

327702

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

327707

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

327722

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.479

High

327723

PRP19
Pre-mRNA-processing factor 19

1

2

High-throughput

0.479

High

327628

GCR
Glucocorticoid receptor

1

0

Small-scale

0.460

High

173548

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

232754

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

317052

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

0

High-throughput

0.458

High

327627

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.458

High

327629

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

327630

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

327632

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

327634

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

327637

EZRI
Ezrin

1

0

High-throughput

0.458

High

327639

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

327641

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

0

High-throughput

0.458

High

327660

CUL3
Cullin-3

1

0

High-throughput

0.458

High

327661

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

1

0

High-throughput

0.458

High

327665

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.458

High

327666

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

327669

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

327676

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

327678

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

327686

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

327690

S7A6O
Probable RNA polymerase II nuclear localization protein SLC7A6OS

1

0

High-throughput

0.458

High

327692

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

0

Small-scale

0.458

High

327695

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

327699

NECD
Necdin

1

0

High-throughput

0.458

High

327704

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

327709

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

327712

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

327713

ANLN
Anillin

1

0

High-throughput

0.458

High

327715

DJC17
DnaJ homolog subfamily C member 17

1

0

High-throughput

0.458

High

327652

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

327708

RPAP3
RNA polymerase II-associated protein 3

1

2

Small-scale

0.445

High

327714

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

327677

CE128
Centrosomal protein of 128 kDa

1

1

High-throughput

0.437

High

327693

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.437

High

327694

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

1

High-throughput

0.437

High

327697

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.437

High

327721

ZNHI2
Zinc finger HIT domain-containing protein 2

3

0

High-throughput

0.350

High

327684

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

327689

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

327674

TTC27
Tetratricopeptide repeat protein 27

2

0

High-throughput

0.318

High

327685

LIPH
Lipase member H

2

0

High-throughput

0.318

High

327644

GRIA2
Glutamate receptor 2

1

0

High-throughput

0.279

Low

327663

PDK3
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

327675

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.279

Low

327647

PSN2
Presenilin-2

1

0

High-throughput

0.251

Low

327636

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

327645

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

0

High-throughput

0.249

Low

327716

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024