Protein: GPHRB
Golgi pH regulator B (Protein GPR89B)

Gene: GPHRB, GPR89B
Organism: Homo sapiens
Interactions: 169
UniProt ID: P0CG08

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0008308 - voltage-gated monoatomic anion channel activity
GO:0015031 - protein transport
GO:0030217 - T cell differentiation
GO:0032580 - Golgi cisterna membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

506610

S39A4
Zinc transporter ZIP4

4

3

High-throughput

0.613

High

251063

B4GT3
Beta-1,4-galactosyltransferase 3

2

0

High-throughput

0.585

High

506605

RABL3
Rab-like protein 3

3

2

High-throughput

0.585

High

506633

LPAR1
Lysophosphatidic acid receptor 1

3

8

High-throughput

0.585

High

506638

TSN17
Tetraspanin-17

3

4

High-throughput

0.585

High

506661

P2Y12
P2Y purinoceptor 12

3

14

High-throughput

0.585

High

506563

CTR1
High affinity cationic amino acid transporter 1

3

6

High-throughput

0.578

High

506570

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

9

High-throughput

0.578

High

506639

BSCL2
Seipin

3

1

High-throughput

0.578

High

506566

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

9

High-throughput

0.558

High

506589

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

2

2

High-throughput

0.558

High

320423

TM63A
Mechanosensitive cation channel TMEM63A

2

2

High-throughput

0.549

High

173843

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

2

3

High-throughput

0.533

High

506552

FPR2
N-formyl peptide receptor 2

2

19

High-throughput

0.533

High

506554

NK1R
Substance-P receptor

2

6

High-throughput

0.533

High

506557

5HT2C
5-hydroxytryptamine receptor 2C

2

3

High-throughput

0.533

High

506562

GRPR
Gastrin-releasing peptide receptor

2

7

High-throughput

0.533

High

506576

AGRE5
Adhesion G protein-coupled receptor E5

2

6

High-throughput

0.533

High

506591

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

1

High-throughput

0.533

High

506599

AAAT
Neutral amino acid transporter B(0)

2

3

High-throughput

0.533

High

506600

C3AR
C3a anaphylatoxin chemotactic receptor

2

15

High-throughput

0.533

High

506612

S39A5
Zinc transporter ZIP5

2

3

High-throughput

0.533

High

506617

S22A9
Organic anion transporter 7

2

4

High-throughput

0.533

High

506621

SC5A8
Sodium-coupled monocarboxylate transporter 1

2

4

High-throughput

0.533

High

506627

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

1

High-throughput

0.533

High

506650

GPR21
Probable G-protein coupled receptor 21

2

7

High-throughput

0.533

High

506657

YIPF3
Protein YIPF3

2

1

High-throughput

0.533

High

506663

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

2

7

High-throughput

0.533

High

506669

IPPK
Inositol-pentakisphosphate 2-kinase

2

1

High-throughput

0.533

High

506682

CLC2D
C-type lectin domain family 2 member D

2

1

High-throughput

0.533

High

506687

GPR52
G-protein coupled receptor 52

2

7

High-throughput

0.533

High

506688

SC6A5
Sodium- and chloride-dependent glycine transporter 2

2

7

High-throughput

0.533

High

395366

ESR1
Estrogen receptor

2

2

High-throughput

0.521

High

506571

EAA3
Excitatory amino acid transporter 3

2

3

High-throughput

0.521

High

506586

CXCR4
C-X-C chemokine receptor type 4

2

12

High-throughput

0.521

High

506597

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

12

High-throughput

0.521

High

506647

SERC2
Serine incorporator 2

2

1

High-throughput

0.521

High

506594

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

1

0

High-throughput

0.513

High

406864

MAS
Proto-oncogene Mas

1

16

High-throughput

0.489

High

506568

APJ
Apelin receptor

1

9

High-throughput

0.489

High

506575

P2RY1
P2Y purinoceptor 1

1

10

High-throughput

0.489

High

506673

SERC1
Serine incorporator 1

1

1

High-throughput

0.489

High

126444

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.479

High

506581

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

506585

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

506592

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

1

High-throughput

0.479

High

506596

MALL
MAL-like protein

1

1

High-throughput

0.479

High

506609

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.479

High

506628

SPP2B
Signal peptide peptidase-like 2B

1

1

High-throughput

0.479

High

506656

TMM59
Transmembrane protein 59

1

1

High-throughput

0.479

High

506659

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.479

High

506674

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

1

High-throughput

0.479

High

506677

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

506616

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

48499

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.437

High

132556

UPK1A
Uroplakin-1a

1

6

High-throughput

0.437

High

134464

CCRL2
C-C chemokine receptor-like 2

1

9

High-throughput

0.437

High

182454

GP182
G-protein coupled receptor 182

1

17

High-throughput

0.437

High

336522

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.437

High

349365

TSN15
Tetraspanin-15

1

4

High-throughput

0.437

High

403764

GCR
Glucocorticoid receptor

1

2

High-throughput

0.437

High

466078

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.437

High

506545

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.437

High

506546

KCNE1
Potassium voltage-gated channel subfamily E member 1

1

1

High-throughput

0.437

High

506550

FPR1
fMet-Leu-Phe receptor

1

17

High-throughput

0.437

High

506551

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

18

High-throughput

0.437

High

506559

NK3R
Neuromedin-K receptor

1

3

High-throughput

0.437

High

506561

V2R
Vasopressin V2 receptor

1

6

High-throughput

0.437

High

506564

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

2

High-throughput

0.437

High

506565

NTR1
Neurotensin receptor type 1

1

6

High-throughput

0.437

High

506569

SCN4A
Sodium channel protein type 4 subunit alpha

1

1

High-throughput

0.437

High

506572

LPAR6
Lysophosphatidic acid receptor 6

1

10

High-throughput

0.437

High

506573

GPR12
G-protein coupled receptor 12

1

7

High-throughput

0.437

High

506574

GLR
Glucagon receptor

1

9

High-throughput

0.437

High

506577

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.437

High

506582

CCR6
C-C chemokine receptor type 6

1

9

High-throughput

0.437

High

506587

RHOA
Transforming protein RhoA

1

4

High-throughput

0.437

High

506588

TSN5
Tetraspanin-5

1

4

High-throughput

0.437

High

506590

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.437

High

506595

TSN31
Tetraspanin-31

1

1

High-throughput

0.437

High

506603

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

1

High-throughput

0.437

High

506608

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

506611

BTNL9
Butyrophilin-like protein 9

1

1

High-throughput

0.437

High

506620

AGRG2
Adhesion G-protein coupled receptor G2

1

4

High-throughput

0.437

High

506624

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.437

High

506626

S7A14
Solute carrier family 7 member 14

1

6

High-throughput

0.437

High

506632

AQP3
Aquaporin-3

1

1

High-throughput

0.437

High

506634

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

506635

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.437

High

506636

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

1

High-throughput

0.437

High

506640

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

506641

CREL1
Protein disulfide isomerase CRELD1

1

3

High-throughput

0.437

High

506642

TM169
Transmembrane protein 169

1

1

High-throughput

0.437

High

506644

DNJC1
DnaJ homolog subfamily C member 1

1

2

High-throughput

0.437

High

506645

OPALI
Opalin

1

1

High-throughput

0.437

High

506648

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

506651

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.437

High

506652

CML1
Chemerin-like receptor 1

1

17

High-throughput

0.437

High

506654

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.437

High

506655

STRA6
Receptor for retinol uptake STRA6

1

1

High-throughput

0.437

High

506658

S22A4
Solute carrier family 22 member 4

1

4

High-throughput

0.437

High

506660

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

506664

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.437

High

506668

AT133
Polyamine-transporting ATPase 13A3

1

5

High-throughput

0.437

High

506670

NCKX3
Sodium/potassium/calcium exchanger 3

1

1

High-throughput

0.437

High

506671

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

7

High-throughput

0.437

High

506676

SC5A4
Probable glucose sensor protein SLC5A4

1

4

High-throughput

0.437

High

506679

TM63C
Osmosensitive cation channel TMEM63C

1

2

High-throughput

0.437

High

506681

LAT2
Large neutral amino acids transporter small subunit 2

1

6

High-throughput

0.437

High

506684

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.437

High

506622

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.426

High

165889

FFAR1
Free fatty acid receptor 1

1

10

High-throughput

0.407

High

303212

S22A5
Organic cation/carnitine transporter 2

1

4

High-throughput

0.407

High

506544

ACHB
Acetylcholine receptor subunit beta

1

2

High-throughput

0.407

High

506553

EDNRA
Endothelin-1 receptor

1

7

High-throughput

0.407

High

506558

AA2BR
Adenosine receptor A2b

1

3

High-throughput

0.407

High

506578

CXCR3
C-X-C chemokine receptor type 3

1

10

High-throughput

0.407

High

506583

CCR9
C-C chemokine receptor type 9

1

10

High-throughput

0.407

High

506619

AGRF3
Adhesion G-protein coupled receptor F3

1

4

High-throughput

0.407

High

506649

S1PR3
Sphingosine 1-phosphate receptor 3

1

7

High-throughput

0.407

High

506653

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.407

High

506685

SC5A6
Sodium-dependent multivitamin transporter

1

4

High-throughput

0.407

High

506630

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

3

0

High-throughput

0.335

High

506643

TXD15
Thioredoxin domain-containing protein 15

2

0

High-throughput

0.318

High

417904

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

506602

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

0

High-throughput

0.279

Low

506666

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

506598

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.269

Low

301312

WFS1
Wolframin

1

0

High-throughput

0.268

Low

217748

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

291192

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

417225

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

506547

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

506548

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

506549

LMNB1
Lamin-B1

1

0

High-throughput

0.249

Low

506556

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

506560

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

506567

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

506579

EMD
Emerin

1

0

High-throughput

0.249

Low

506580

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.249

Low

506584

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

506593

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.249

Low

506601

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

506604

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

506607

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

506613

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

506614

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.249

Low

506615

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

506625

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

506646

PIGS
GPI-anchor transamidase component PIGS

1

0

High-throughput

0.249

Low

506662

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

506665

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

506667

FNDC4
Fibronectin type III domain-containing protein 4

1

0

High-throughput

0.249

Low

506672

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

506675

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

506678

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

506683

ALK
ALK tyrosine kinase receptor

1

0

Small-scale

0.249

Low

506686

DJC16
DnaJ homolog subfamily C member 16

1

0

High-throughput

0.249

Low

49728

TMM72
Transmembrane protein 72

1

0

High-throughput

0.232

Low

125001

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.232

Low

190544

COPT2
Protein SLC31A2

1

0

High-throughput

0.232

Low

506555

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.232

Low

506606

GP107
Protein GPR107

1

0

High-throughput

0.232

Low

506618

CA210
Type III endosome membrane protein TEMP

1

0

High-throughput

0.232

Low

506623

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low

506629

GPBAR
G-protein coupled bile acid receptor 1

1

0

High-throughput

0.232

Low

506631

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.232

Low

506637

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

506680

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025