HitPredict

Interactor 1: POTEI (P0CG38)
POTE ankyrin domain family member I
Gene: POTEI

Interactor 2: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30890647, 35575683
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005884 - actin filament GO:0015629 - actin cytoskeleton GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1075 Hs			1 377
+	Hs
		506940 POTEI_HUMAN (1-1075): 0: 1117: 100.00		ACTS_HUMAN (1-377): 0: 599: 98.94
+	Hs
		506935 POTEI_HUMAN (1-1075): 0: 1117: 100.00		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		506937 POTEI_HUMAN (1-1075): 0: 1117: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		506936 POTEI_HUMAN (1-1075): 0: 1117: 100.00		ACTA_HUMAN (1-377): 0: 597: 98.41
+	Hs
		995650 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		996478 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTS_HUMAN (1-377): 0: 599: 98.94
+	Hs
		952905 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		993220 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		977731 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTA_HUMAN (1-377): 0: 597: 98.41
+	Hs
		506938 POTEI_HUMAN (1-1075): 0: 1117: 100.00		ACTH_HUMAN (4-377): 0: 591: 98.93
+	Hs
		62932 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		62933 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTS_HUMAN (1-377): 0: 599: 98.94
+	Hs
		62924 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		62930 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		62928 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTA_HUMAN (1-377): 0: 597: 98.41
+	Hs
		993427 POTEE_HUMAN (1-1075): 0: 1112: 97.02		ACTH_HUMAN (4-377): 0: 591: 98.93
+	Hs
		62931 POTEF_HUMAN (1-1074): 0: 1109: 96.83		ACTH_HUMAN (4-377): 0: 591: 98.93
+	Hs
		507015 POTEJ_HUMAN (1-1075): 0: 1067: 95.72		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		507018 POTEJ_HUMAN (1-1075): 0: 1067: 95.72		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		507017 POTEJ_HUMAN (1-1075): 0: 1067: 95.72		ACTA_HUMAN (1-377): 0: 597: 98.41