Protein: ACTH
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]

Gene: ACTH, ACTG2
Organism: Homo sapiens
Interactions: 66
UniProt ID: P63267

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

952726

ACTB
Actin, cytoplasmic 1

3

20

High-throughput

0.827

High

993124

ACTG
Actin, cytoplasmic 2

2

20

High-throughput

0.754

High

908944

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.691

High

993437

IGSF8
Immunoglobulin superfamily member 8

1

5

High-throughput

0.691

High

62931

POTEF
POTE ankyrin domain family member F

1

20

High-throughput

0.618

High

506938

POTEI
POTE ankyrin domain family member I

1

20

High-throughput

0.618

High

507019

POTEJ
POTE ankyrin domain family member J

1

20

High-throughput

0.618

High

660029

COF1
Cofilin-1

1

20

High-throughput

0.618

High

773153

MYH10
Myosin-10

1

14

High-throughput

0.618

High

974919

TYB4
Thymosin beta-4

1

6

High-throughput

0.618

High

977668

ACTA
Actin, aortic smooth muscle

1

19

High-throughput

0.618

High

993412

ACTH
Actin, gamma-enteric smooth muscle

1

16

High-throughput

0.618

High

993413

ACTC
Actin, alpha cardiac muscle 1

1

16

High-throughput

0.618

High

993414

ACTS
Actin, alpha skeletal muscle

1

16

High-throughput

0.618

High

993417

CAP1
Adenylyl cyclase-associated protein 1

1

20

High-throughput

0.618

High

993422

PLEC
Plectin

1

20

High-throughput

0.618

High

993424

ACTBL
Beta-actin-like protein 2

1

16

High-throughput

0.618

High

993425

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.618

High

993427

POTEE
POTE ankyrin domain family member E

1

17

High-throughput

0.618

High

993430

MYH14
Myosin-14

1

14

High-throughput

0.618

High

993431

ALPK2
Alpha-protein kinase 2

1

8

High-throughput

0.618

High

993440

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

6

High-throughput

0.618

High

993443

TRIM6
Tripartite motif-containing protein 6

2

10

Small-scale

0.584

High

993418

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

8

High-throughput

0.575

High

894674

EMD
Emerin

1

1

Small-scale

0.561

High

355187

ACL6A
Actin-like protein 6A

1

19

High-throughput

0.553

High

563597

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

732529

ARRB2
Beta-arrestin-2

1

6

High-throughput

0.536

High

993416

ANK2
Ankyrin-2

1

6

High-throughput

0.536

High

827375

MLH1
DNA mismatch repair protein Mlh1

1

2

Small-scale

0.508

High

635517

NEBU
Nebulin

1

20

Small-scale

0.501

High

993433

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

1

High-throughput

0.489

High

993438

FAF2
FAS-associated factor 2

1

5

High-throughput

0.489

High

407802

SHBG
Sex hormone-binding globulin

1

3

Small-scale

0.481

High

140859

NOP56
Nucleolar protein 56

1

2

Small-scale

0.479

High

324762

HEXI1
Protein HEXIM1

1

6

High-throughput

0.479

High

543166

UBL4A
Ubiquitin-like protein 4A

1

11

High-throughput

0.479

High

641555

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

13

High-throughput

0.479

High

651268

CBL
E3 ubiquitin-protein ligase CBL

1

13

Small-scale

0.479

High

887950

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.479

High

970294

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

993415

RED1
Double-stranded RNA-specific editase 1

1

12

High-throughput

0.479

High

993421

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

993423

LARP7
La-related protein 7

1

12

High-throughput

0.479

High

993428

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

993436

KAT5
Histone acetyltransferase KAT5

1

11

High-throughput

0.479

High

993439

CI072
Guanine nucleotide exchange factor C9orf72

1

5

High-throughput

0.479

High

993441

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.479

High

993445

PLPL8
Calcium-independent phospholipase A2-gamma

1

3

Small-scale

0.479

High

993446

LIMA1
LIM domain and actin-binding protein 1

1

16

High-throughput

0.479

High

993447

ERRFI
ERBB receptor feedback inhibitor 1

1

10

High-throughput

0.479

High

987520

GRB2
Growth factor receptor-bound protein 2

1

14

High-throughput

0.445

High

993420

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

8

Small-scale

0.437

High

993426

OTUD1
OTU domain-containing protein 1

1

2

High-throughput

0.437

High

993429

MEPCE
7SK snRNA methylphosphate capping enzyme

1

6

High-throughput

0.437

High

993432

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

20

Small-scale

0.437

High

779701

MOT8
Monocarboxylate transporter 8

1

3

High-throughput

0.407

High

993435

SPX3
Sugar phosphate exchanger 3

1

2

High-throughput

0.407

High

993442

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

3

High-throughput

0.407

High

993449

FLVC1
Choline/ethanolamine transporter FLVCR1

1

3

High-throughput

0.407

High

292273

S22A3
Solute carrier family 22 member 3

1

0

High-throughput

0.232

Low

993419

NTCP7
Sodium/bile acid cotransporter 7

1

0

High-throughput

0.232

Low

993434

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

Small-scale

0.232

Low

993444

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.232

Low

993448

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025