Protein: POTEE
POTE ankyrin domain family member E (ANKRD26-like family C member 1A) (Prostate, ovary, testis-expressed protein on chromosome 2) (POTE-2)

Gene: POTEE
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q6S8J3

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005884 - actin filament
GO:0007409 - axonogenesis
GO:0015629 - actin cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567892

PRG2
Bone marrow proteoglycan

3

7

High-throughput

0.861

High

952905

ACTB
Actin, cytoplasmic 1

3

20

High-throughput

0.847

High

270372

WDR1
WD repeat-containing protein 1

2

14

High-throughput

0.811

High

993220

ACTG
Actin, cytoplasmic 2

2

20

High-throughput

0.789

High

354721

PAK4
Serine/threonine-protein kinase PAK 4

1

2

High-throughput

0.691

High

909054

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.691

High

1247533

CLC2D
C-type lectin domain family 2 member D

1

5

High-throughput

0.691

High

719960

HMOX2
Heme oxygenase 2

3

0

High-throughput

0.638

High

303708

CYTF
Cystatin-F

2

1

High-throughput

0.628

High

481314

HMGB1
High mobility group protein B1

2

6

High-throughput

0.628

High

666108

PPAC
Low molecular weight phosphotyrosine protein phosphatase

2

1

High-throughput

0.628

High

1030831

DEF6
Defensin-6

2

1

High-throughput

0.628

High

1247500

CBPA5
Carboxypeptidase A5

2

1

High-throughput

0.628

High

1247516

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

2

18

High-throughput

0.628

High

688579

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

4

High-throughput

0.618

High

841557

I12R1
Interleukin-12 receptor subunit beta-1

1

1

High-throughput

0.618

High

272271

OBSL1
Obscurin-like protein 1

1

8

High-throughput

0.618

High

331063

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.618

High

506964

POTEI
POTE ankyrin domain family member I

1

20

High-throughput

0.618

High

507033

POTEJ
POTE ankyrin domain family member J

1

19

High-throughput

0.618

High

581125

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.618

High

584560

VAV
Proto-oncogene vav

1

18

High-throughput

0.618

High

641616

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

16

High-throughput

0.618

High

977731

ACTA
Actin, aortic smooth muscle

1

20

High-throughput

0.618

High

993427

ACTH
Actin, gamma-enteric smooth muscle

1

17

High-throughput

0.618

High

995650

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.618

High

996478

ACTS
Actin, alpha skeletal muscle

1

17

High-throughput

0.618

High

1004098

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.618

High

1034005

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

8

High-throughput

0.618

High

1035711

KIF23
Kinesin-like protein KIF23

1

7

High-throughput

0.618

High

1045419

TF65
Transcription factor p65

1

9

Small-scale

0.618

High

1140444

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.618

High

1200979

ACTBL
Beta-actin-like protein 2

1

20

High-throughput

0.618

High

1247520

ECT2
Protein ECT2

1

20

High-throughput

0.618

High

1247522

RHOF
Rho-related GTP-binding protein RhoF

1

13

High-throughput

0.618

High

1247524

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

6

High-throughput

0.618

High

1247531

HDAC6
Protein deacetylase HDAC6

1

8

High-throughput

0.618

High

835487

CCR2
C-C chemokine receptor type 2

2

3

High-throughput

0.612

High

1247523

GPR35
G-protein coupled receptor 35

3

11

High-throughput

0.609

High

1247498

CHSTE
Carbohydrate sulfotransferase 14

2

0

High-throughput

0.602

High

1247517

PDGFD
Platelet-derived growth factor D

2

0

High-throughput

0.602

High

1247527

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

1108570

TBB3
Tubulin beta-3 chain

1

8

High-throughput

0.575

High

1247490

TBA1A
Tubulin alpha-1A chain

1

8

High-throughput

0.575

High

1247486

I27RA
Interleukin-27 receptor subunit alpha

2

6

High-throughput

0.574

High

396354

ESR1
Estrogen receptor

2

13

High-throughput

0.571

High

838941

RHG25
Rho GTPase-activating protein 25

1

19

High-throughput

0.553

High

1027962

ECT2L
Epithelial cell-transforming sequence 2 oncogene-like

1

19

High-throughput

0.553

High

1241888

FBX42
F-box only protein 42

1

4

High-throughput

0.553

High

1247489

RHG36
Rho GTPase-activating protein 36

1

18

High-throughput

0.553

High

1247536

FBXL4
F-box/LRR-repeat protein 4

1

2

High-throughput

0.553

High

210758

KLK10
Kallikrein-10

1

4

High-throughput

0.536

High

663498

PRPH2
Peripherin-2

1

2

High-throughput

0.536

High

664060

PRTN3
Myeloblastin

1

6

High-throughput

0.536

High

880449

RPIA
Ribose-5-phosphate isomerase

1

1

High-throughput

0.536

High

945935

LOXL3
Lysyl oxidase homolog 3

1

2

High-throughput

0.536

High

1007572

PRAME
Melanoma antigen preferentially expressed in tumors

1

3

High-throughput

0.536

High

1034756

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.536

High

1052044

CALD1
Caldesmon

1

20

High-throughput

0.536

High

1245860

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.536

High

1247487

ALKL2
ALK and LTK ligand 2

1

1

High-throughput

0.536

High

1247488

TRI72
Tripartite motif-containing protein 72

1

11

High-throughput

0.536

High

1247518

CST11
Cystatin-11

1

1

High-throughput

0.536

High

1247537

KLK9
Kallikrein-9

1

4

High-throughput

0.536

High

51088

PKHG3
Pleckstrin homology domain-containing family G member 3

2

16

High-throughput

0.521

High

1155473

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.515

High

1247506

Q96D37
VAV1 protein

1

18

High-throughput

0.514

High

178639

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.513

High

1149916

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.513

High

1247495

IFNE
Interferon epsilon

1

0

High-throughput

0.513

High

1247525

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1247532

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.513

High

324002

CSTN1
Calsyntenin-1

1

3

High-throughput

0.489

High

1236101

FSTL4
Follistatin-related protein 4

1

3

High-throughput

0.489

High

1247504

ESPB1
Epididymal sperm-binding protein 1

1

4

High-throughput

0.489

High

1247539

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.489

High

1247543

AP4B1
AP-4 complex subunit beta-1

1

2

High-throughput

0.489

High

135252

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

14

High-throughput

0.479

High

177386

ARHGB
Rho guanine nucleotide exchange factor 11

1

15

High-throughput

0.479

High

247968

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

324938

HEXI1
Protein HEXIM1

1

9

High-throughput

0.479

High

402383

GBA1
Lysosomal acid glucosylceramidase

1

1

Small-scale

0.479

High

464990

SP1
Transcription factor Sp1

1

5

Small-scale

0.479

High

535200

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

862236

YAP1
Transcriptional coactivator YAP1

1

18

High-throughput

0.479

High

937276

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

18

High-throughput

0.479

High

980862

H2B1C
Histone H2B type 1-C/E/F/G/I

1

3

High-throughput

0.479

High

1056803

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.479

High

1105974

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

4

High-throughput

0.479

High

1144381

NONO
Non-POU domain-containing octamer-binding protein

1

6

Small-scale

0.479

High

1220575

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1247494

ARHGP
Rho guanine nucleotide exchange factor 25

1

12

High-throughput

0.479

High

1247501

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1247508

FGD4
FYVE, RhoGEF and PH domain-containing protein 4

1

16

High-throughput

0.479

High

1247511

PHB2
Prohibitin-2

1

5

High-throughput

0.479

High

1247519

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

1247521

RC3H2
Roquin-2

1

14

High-throughput

0.479

High

1247526

ANLN
Anillin

1

10

High-throughput

0.479

High

1247529

MTCH1
Mitochondrial carrier homolog 1

1

2

High-throughput

0.479

High

1247534

PFD2
Prefoldin subunit 2

1

3

High-throughput

0.479

High

1247535

ERRFI
ERBB receptor feedback inhibitor 1

1

11

High-throughput

0.479

High

1247540

LOXL2
Lysyl oxidase homolog 2

1

2

High-throughput

0.479

High

1247542

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

11

Small-scale

0.479

High

418213

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

1234828

PKHA7
Pleckstrin homology domain-containing family A member 7

1

15

High-throughput

0.445

High

1247510

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

12

High-throughput

0.445

High

106129

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

765635

BMI1
Polycomb complex protein BMI-1

1

18

High-throughput

0.437

High

914203

EFNA3
Ephrin-A3

1

4

High-throughput

0.437

High

965037

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.437

High

1086245

TFCP2
Alpha-globin transcription factor CP2

1

7

High-throughput

0.437

High

1194160

LARP7
La-related protein 7

1

14

High-throughput

0.437

High

1240290

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.437

High

1247491

MEPCE
7SK snRNA methylphosphate capping enzyme

1

9

High-throughput

0.437

High

1247493

SLN11
Schlafen family member 11

1

2

Small-scale

0.437

High

1247505

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.437

High

1247507

SPDLY
Protein Spindly

1

17

High-throughput

0.437

High

1247515

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.437

High

1247528

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

1

High-throughput

0.437

High

1247530

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.437

High

1247538

PKHG1
Pleckstrin homology domain-containing family G member 1

1

14

High-throughput

0.437

High

1247541

NGN3
Neurogenin-3

1

5

Small-scale

0.437

High

1247497

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.426

High

1097366

CBX3
Chromobox protein homolog 3

1

2

Small-scale

0.407

High

1103239

CTBP1
C-terminal-binding protein 1

1

8

High-throughput

0.407

High

1212978

Q5T5D8
Zinc finger protein 684

1

1

High-throughput

0.407

High

1247502

PMM1
Phosphomannomutase 1

3

0

High-throughput

0.347

High

337421

TGDS
dTDP-D-glucose 4,6-dehydratase

2

0

High-throughput

0.328

High

1247503

TM186
Transmembrane protein 186

2

0

High-throughput

0.328

High

1247514

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.328

High

1212973

ZN684
Zinc finger protein 684

2

0

High-throughput

0.318

High

49924

S66AL
Putative uncharacterized protein SLC66A1LP

1

0

High-throughput

0.279

Low

403082

REL2
Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

1216349

ZC21B
Zinc finger C2HC domain-containing protein 1B

1

0

High-throughput

0.279

Low

1247492

CE024
UPF0461 protein C5orf24

1

0

High-throughput

0.279

Low

1247499

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.279

Low

1247512

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1247513

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.279

Low

1247509

MOGT1
2-acylglycerol O-acyltransferase 1

1

0

High-throughput

0.269

Low

361642

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.249

Low

1240637

CDC73
Parafibromin

1

0

High-throughput

0.249

Low

1247496

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025