HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.685

Property	Details
Experiments	31980649, 40437099, 20936779, unassigned2173
Identification Methods	affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 192
+	Hs
		507751 UBC_HUMAN (1-685): 0: 857: 100.00		CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31
+	Hs
		507834 UBC_HUMAN (1-685): 0: 857: 100.00		RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35
+	Hs
		507764 UBC_HUMAN (1-685): 0: 857: 100.00		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Rn
		1224463 UBC_RAT (1-637): 0: 779: 98.90		RAC1_RAT (1-192): 4.32e-85: 250: 100.00
+	Rn
		1224483 UBC_RAT (1-637): 0: 779: 98.90		CDC42_RAT (1-192): 5.32e-78: 232: 70.31
+	Rn
		1181566 UBC_RAT (1-637): 0: 779: 98.90		Q32PX6_RAT (1-192): 1.18e-77: 231: 71.35
+	Dm
		509791 UBIQP_DROME (1-610): 0: 759: 99.84		RAC1_DROME (1-192): 8.88e-82: 242: 91.67
+	Hs
		986978 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Mm
		509019 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RAC1_MOUSE (1-192): 4.32e-85: 250: 100.00
+	Hs
		961932 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98
+	Hs
		507151 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00
+	Hs
		507369 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64