Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: KPYM (P14618)
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)
Gene: PKM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 25263439, 32572027
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 822
Hs

1 531
+ Hs
+ Hs

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Last updated: 15 Jul 2024