HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: KALM (P23352)
Anosmin-1 (Adhesion molecule-like X-linked) (Kallmann syndrome protein)
Gene: ANOS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.904

The method score is based on:

Property Details
Experiments 15548653, 19696444, 20874775, 23189990
Identification Methods pull down, affinity chromatography technology, cross-linking study, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~fn3, fn3~ig, PK_Tyr_Ser-Thr~fn3
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0008201 - heparin binding
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 822
Hs

1 680
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024