HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	18022941, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 1224
+	Hs
		665461 EPHA8_HUMAN (3-819): 0: 603: 19.35		COPA_HUMAN (1-1224): 0: 1334: 100.00
+	Hs
		863448 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		COPA_HUMAN (1-1224): 0: 1334: 100.00
+	Hs
		384549 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		COPA_HUMAN (1-1224): 0: 1334: 100.00
+	Hs
		729253 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		COPA_HUMAN (1-1224): 0: 1334: 100.00
+	Hs
		507887 FGFR1_HUMAN (1-822): 0: 861: 100.00		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		609202 FGFR3_HUMAN (6-821): 0: 730: 61.22		LIS1_HUMAN (359-573): 1.07e-16: 85.8: 13.10
+	Hs
		725452 EPHA7_HUMAN (3-783): 0: 629: 19.40		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		665444 EPHA8_HUMAN (3-819): 0: 603: 19.35		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		725460 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		674357 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		LIS1_HUMAN (359-573): 1.07e-16: 85.8: 13.10
+	Hs
		384438 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		LIS1_HUMAN (359-573): 1.07e-16: 85.8: 13.10
+	Hs
		384386 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		384596 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		WDR5_HUMAN (520-631): 6.51e-11: 67.4: 10.35
+	Hs
		738171 FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47		LIS1_HUMAN (359-573): 1.07e-16: 85.8: 13.10
+	Hs
		972377 TIE2_HUMAN (484-771): 3.85e-69: 250: 45.52		WDR3_HUMAN (427-714): 2.55e-18: 93.2: 14.15
+	Hs
		572595 VGFR1_HUMAN (48-362): 8.54e-23: 107: 18.73		LIS1_HUMAN (359-573): 1.07e-16: 85.8: 13.10
+	Hs
		725373 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53