Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A
Interactor 2: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.33 | 1.00 | 0.575 |
The method score is based on:
Property | Details |
---|---|
Experiments | 9972548 |
Identification Methods | x-ray crystallography |
Interaction Type | association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | DNA_gyraseB~DNA_gyraseB, DNA_gyraseB~DNA_topoisoIV, DNA_gyraseB~HATPase_c, DNA_gyraseB~Toprim, DNA_topoisoIV~DNA_topoisoIV, DNA_topoisoIV~Toprim, DNA_topoisoIV~TOPRIM_C, HATPase_c~HATPase_c, Toprim~Toprim, TOPRIM_C~Toprim |
Common GO terms | GO:0000287 - magnesium ion binding GO:0000712 - resolution of meiotic recombination intermediates GO:0000775 - chromosome, centromeric region GO:0000793 - condensed chromosome GO:0000819 - sister chromatid segregation and 33 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024