HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: HDAC6 (Q9Z2V5)
Protein deacetylase HDAC6 (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) (mHDA2)
Gene: HDAC6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	16810319, 28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-UBP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 1149
+	Hs
		508764 UBC_HUMAN (77-724): 0: 798: 97.22		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		987256 RS27A_HUMAN (609-684): 3.68e-42: 152: 100.00		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		182005 UBD_HUMAN (155-304): 2.53e-28: 113: 32.05		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		507401 UBB_HUMAN (1-77): 1.49e-27: 113: 98.70		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		1109789 Q59EM9_HUMAN (76-724): 0: 802: 97.07		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		507934 UBC_HUMAN (77-724): 0: 798: 97.22		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		508368 UBC_HUMAN (77-724): 0: 798: 97.22		HDAC2_HUMAN (77-488): 7.68e-156: 475: 21.89
+	Hs
		508334 UBC_HUMAN (77-724): 0: 798: 97.22		HDAC7_HUMAN (439-886): 3.69e-144: 460: 36.82
+	Hs
		507739 UBC_HUMAN (77-724): 0: 798: 97.22		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	At
		198826 UBQ3_ARATH (457-724): 3.94e-100: 312: 89.55		HDA19_ARATH (87-463): 1.19e-129: 407: 22.14
+	Hs
		987014 RS27A_HUMAN (609-684): 3.68e-42: 152: 100.00		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		940906 RS27A_HUMAN (609-684): 3.68e-42: 152: 100.00		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Zm
		21392 B6SKC9_MAIZE (1-153): 5.87e-22: 102: 26.75		A0A1D6HSW2_MAIZE (82-470): 5.1e-133: 420: 36.55