HitPredict

Interactor 1: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Interactor 2: FLI1 (Q01543)
Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB)
Gene: FLI1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 35140242, 9681824
Identification Methods proximity labelling technology, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ets~Ets, SAM_PNT~SAM_PNT
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 6 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 479
Hs

1 452
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024